Carrie Newlands , Elizabeth Gruber , Franel Le Grange , Rajiv Anand , Simon Whitley , Stephen Keohane
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Responses were analysed using online SurveyMonkey tools.</div></div><div><h3>Results</h3><div>105 consultant members of a relevant MDT responded, including 19 skin and 2 sarcoma MDT Chairs. There was widespread variation in referral pathways, with 25.7% of participants reporting no sarcoma MDT involvement in a hypothetical case of a patient with a 2.1 cm primary PDS of the scalp, with no clinically apparent regional or distant metastases (N0M0). Opinions on the correct peripheral and deep surgical excision margins (PM/DM) varied, with the majority choosing a 10 mm PM (53.3%). Taking periosteum as the deep margin was preferred by 50.5%. Histological clearance margins of at least 5 mm at the PM and at least 1 mm at the DM were preferred by 33.3% of participants and deemed to be acceptable as definitive treatment. Imaging at diagnosis and for surveillance showed wide variation, with 24.8% not offering any imaging at diagnosis, in the above case.</div></div><div><h3>Conclusions</h3><div>PDS pathways and clinical management have been shown to vary widely amongst UK MDT members. A modified Delphi study is proposed to develop consensus-based guidance.</div></div>","PeriodicalId":100278,"journal":{"name":"Clinical Surgical Oncology","volume":"3 4","pages":"Article 100061"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pleomorphic dermal sarcoma. UK multidisciplinary team members have wide variation in opinions on management and pathways\",\"authors\":\"Carrie Newlands , Elizabeth Gruber , Franel Le Grange , Rajiv Anand , Simon Whitley , Stephen Keohane\",\"doi\":\"10.1016/j.cson.2024.100061\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Pleomorphic Dermal Sarcoma (PDS) is increasing in incidence and evidence-based guidelines as to optimal management are lacking. It is unclear from guidance which cancer MDTs should be involved in the care of patients with PDS and there is anecdotally widespread variation in patient pathways and management.</div></div><div><h3>Objective</h3><div>To determine current pathways and opinions regarding management of PDS amongst members of relevant UK MDTs.</div></div><div><h3>Methods</h3><div>A survey was devised, piloted, and circulated to MDT members, via national organisations. Responses were analysed using online SurveyMonkey tools.</div></div><div><h3>Results</h3><div>105 consultant members of a relevant MDT responded, including 19 skin and 2 sarcoma MDT Chairs. There was widespread variation in referral pathways, with 25.7% of participants reporting no sarcoma MDT involvement in a hypothetical case of a patient with a 2.1 cm primary PDS of the scalp, with no clinically apparent regional or distant metastases (N0M0). Opinions on the correct peripheral and deep surgical excision margins (PM/DM) varied, with the majority choosing a 10 mm PM (53.3%). Taking periosteum as the deep margin was preferred by 50.5%. Histological clearance margins of at least 5 mm at the PM and at least 1 mm at the DM were preferred by 33.3% of participants and deemed to be acceptable as definitive treatment. Imaging at diagnosis and for surveillance showed wide variation, with 24.8% not offering any imaging at diagnosis, in the above case.</div></div><div><h3>Conclusions</h3><div>PDS pathways and clinical management have been shown to vary widely amongst UK MDT members. A modified Delphi study is proposed to develop consensus-based guidance.</div></div>\",\"PeriodicalId\":100278,\"journal\":{\"name\":\"Clinical Surgical Oncology\",\"volume\":\"3 4\",\"pages\":\"Article 100061\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Surgical Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2773160X24000291\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Surgical Oncology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2773160X24000291","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:多形性真皮肉瘤(PDS)的发病率正在增加,缺乏循证的最佳治疗指南。从指南中还不清楚哪些癌症MDTs应该参与PDS患者的护理,而且在患者途径和管理方面存在广泛的差异。目的确定英国相关MDTs成员对PDS管理的当前途径和意见。方法通过国家组织设计、试点并向MDT成员分发了一项调查。使用在线SurveyMonkey工具对反馈进行分析。结果105名相关MDT顾问成员回应,包括19名皮肤MDT主席和2名肉瘤MDT主席。转诊途径存在广泛的差异,在一个假设的2.1厘米原发头皮PDS患者病例中,有25.7%的参与者报告没有肉瘤MDT涉及,没有临床明显的区域或远处转移(N0M0)。对正确的外周和深部手术切除边缘(PM/DM)的看法不一,大多数人选择10 mm PM(53.3%)。50.5%的人选择骨膜作为深缘。33.3%的参与者认为PM的组织学清除率至少为5 mm, DM的组织学清除率至少为1 mm,这被认为是可以接受的最终治疗。在上述病例中,诊断时的影像学和监测时的影像学差异很大,有24.8%的患者在诊断时不提供任何影像学。结论:在英国MDT成员中,spds通路和临床管理存在很大差异。提出了一种改进的德尔菲研究,以制定基于共识的指导。
Pleomorphic dermal sarcoma. UK multidisciplinary team members have wide variation in opinions on management and pathways
Background
Pleomorphic Dermal Sarcoma (PDS) is increasing in incidence and evidence-based guidelines as to optimal management are lacking. It is unclear from guidance which cancer MDTs should be involved in the care of patients with PDS and there is anecdotally widespread variation in patient pathways and management.
Objective
To determine current pathways and opinions regarding management of PDS amongst members of relevant UK MDTs.
Methods
A survey was devised, piloted, and circulated to MDT members, via national organisations. Responses were analysed using online SurveyMonkey tools.
Results
105 consultant members of a relevant MDT responded, including 19 skin and 2 sarcoma MDT Chairs. There was widespread variation in referral pathways, with 25.7% of participants reporting no sarcoma MDT involvement in a hypothetical case of a patient with a 2.1 cm primary PDS of the scalp, with no clinically apparent regional or distant metastases (N0M0). Opinions on the correct peripheral and deep surgical excision margins (PM/DM) varied, with the majority choosing a 10 mm PM (53.3%). Taking periosteum as the deep margin was preferred by 50.5%. Histological clearance margins of at least 5 mm at the PM and at least 1 mm at the DM were preferred by 33.3% of participants and deemed to be acceptable as definitive treatment. Imaging at diagnosis and for surveillance showed wide variation, with 24.8% not offering any imaging at diagnosis, in the above case.
Conclusions
PDS pathways and clinical management have been shown to vary widely amongst UK MDT members. A modified Delphi study is proposed to develop consensus-based guidance.