妊娠期糖尿病的综合综述:病理生理学,药理管理和药学服务的作用。

IF 1.1 Q4 PHARMACOLOGY & PHARMACY
Abdulkadir Abdu, Hossamaldeen Bakrey
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引用次数: 0

摘要

本文综述了药物治疗在治疗妊娠期糖尿病(GDM)中所起的重要作用,从而提高对母亲和儿童的治疗效果。讨论GDM的频率和相关性将有助于强调良好管理的必要性。病理生理学展示了对基本过程的彻底检查,阐明了怀孕期间激素变化如何导致胰岛素抵抗和血糖水平升高。本文探讨了糖尿病的药物治疗途径,包括胰岛素治疗和口服降糖药。考虑到产生出生畸形的危害和安全性数据,本文还评价了药物在糖尿病妊娠中的安全性,以期提供最佳的治疗效果。此外,药剂师在GDM中的作用突出了他们在患者教育、确保药物依从性和与多学科团队合作监督治疗方面的重要性。此外,药学服务对孕产妇和新生儿结局的影响表明,药物干预可以有效减少子痫前期和新生儿低血糖等并发症,突出了个性化用药管理的重要性。最后,GDM的挑战和未来方向解决了药学服务中的困难,包括患者依从性、医疗保健可及性和新兴治疗方法,呼吁开展更多的研究和政策举措,以改善药学服务框架,提高母婴健康结果。这篇综合综述强调了在管理GDM方面需要综合药学服务,以及GDM改善母亲和婴儿健康结局的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comprehensive Review of Gestational Diabetes: Pathophysiology, Pharmacological Management and the Role of Pharmaceutical Care.

This review addresses the significant part pharmacological treatment plays in treating gestational diabetes mellitus (GDM), therefore enhancing the results for mother and child. Talking about the frequency and relevance of GDM would help to underline the need for good management. The pathophysiology presents a thorough examination of the fundamental processes, clarifying how hormonal changes seen during pregnancy lead to insulin resistance and raised blood sugar levels. The pharmacological treatment approaches for GDM, including insulin treatment and oral hypoglycemic medications, are investigated in this paper. Taking into consideration the hazards of generating birth deformities and safety data, the paper also evaluates the safety of the drugs in diabetes pregnancy in order to offer best treatment results. Moreover, the function of pharmacists in GDM highlights their significance in patient education, ensuring adherence to medication and overseeing therapy in collaboration with multidisciplinary teams. Furthermore, the impact of pharmaceutical care on maternal and neonatal outcomes demonstrates how pharmaceutical interventions can effectively reduce complications like preeclampsia and neonatal hypoglycemia, highlighting the importance of personalized medication management. Finally, the challenges and future directions of GDM address the difficulties in pharmaceutical care, including patient compliance, healthcare access and emerging treatment methods, calling for more research and policy initiatives to improve pharmaceutical care frameworks and enhance health outcomes for both mothers and infants. This comprehensive review highlights the need for integrated pharmaceutical care in managing GDM and its potential to improve health outcomes for both mothers and infants.

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来源期刊
Current drug safety
Current drug safety PHARMACOLOGY & PHARMACY-
CiteScore
2.10
自引率
0.00%
发文量
112
期刊介绍: Current Drug Safety publishes frontier articles on all the latest advances on drug safety. The journal aims to publish the highest quality research articles, reviews and case reports in the field. Topics covered include: adverse effects of individual drugs and drug classes, management of adverse effects, pharmacovigilance and pharmacoepidemiology of new and existing drugs, post-marketing surveillance. The journal is essential reading for all researchers and clinicians involved in drug safety.
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