具有红光触发光热和光敏特性的负载并五苯的发光碳纳米点

IF 3 4区化学 Q3 CHEMISTRY, PHYSICAL

ChemPhotoChem Pub Date : 2024-10-08 DOI:10.1002/cptc.202400167

Giuseppe Forte, Grazia M. L. Consoli, Loredana Ferreri, Ludovica Maugeri, Alice Foti, Cristina Satriano, Giorgia Fangano, Salvatore Petralia

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引用次数: 0

摘要

开发用于光致热和光动力效应的多功能纳米系统是生物医学领域应用的先进材料研究中的一个具有挑战性的课题。本文报道了用聚n-异丙基丙烯酰胺聚合物（CDs-PNM）包覆并五苯（PTC）制备的红致发光碳纳米点（CDs-PNM/PTC）。采用紫外-可见分光光度法、荧光、核磁共振、原子力显微镜等技术对CD-PNM/PTC纳米体系进行了表征。通过分子模拟研究揭示了CD-PNM/PTC超分子加合物在298 K和315 K下的稳定性、结构和能量。纳米cd - pnm /PTC在680 nm处具有优异的水分散性、良好的光热转换效率和光敏效果。无明显毒性和真核细胞摄取是光热-光动力处理的潜在应用特点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Luminescent Pentacene-Loaded Carbon Nanodots with Red-Light Triggered Photothermal and Photosensitizing Properties

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Luminescent Pentacene-Loaded Carbon Nanodots with Red-Light Triggered Photothermal and Photosensitizing Properties

The development of multifunctional nanosystems for photo-induced hyperthermia and photodynamic effect is a challenging topic in the research of advanced materials for application in biomedical field. Here, we report red-luminescent carbon-nanodots (CDs-PNM/PTC) derived from entrapment of pentacene (PTC) in nanodots prepared from poly(N-isopropylacrylamide) polymer (CDs-PNM) by an easy and reagent-free method. The CD-PNM/PTC nanosystem was characterized by different techniques (UV-Vis spectrophotometry, fluorescence, NMR, AFM). Molecular modelling investigations were performed to unveil stability, structures and energy of the CD-PNM/PTC supramolecular adducts at 298 K and 315 K. The nanosized CDs-PNM/PTC exhibited excellent water-dispersibility, good photothermal conversion efficiency and photosensitizing effect at 680 nm. No significant toxicity and eukaryotic cell uptake are features that open to potential applications in photothermal-photodynamic treatments.

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来源期刊

ChemPhotoChem Chemistry-Physical and Theoretical Chemistry

CiteScore

5.80

自引率

5.40%

发文量

165

期刊介绍： Light plays a crucial role in natural processes and leads to exciting phenomena in molecules and materials. ChemPhotoChem welcomes exceptional international research in the entire scope of pure and applied photochemistry, photobiology, and photophysics. Our thorough editorial practices aid us in publishing authoritative research fast. We support the photochemistry community to be a leading light in science. We understand the huge pressures the scientific community is facing every day and we want to support you. Chemistry Europe is an association of 16 chemical societies from 15 European countries. Run by chemists, for chemists—we evaluate, publish, disseminate, and amplify the scientific excellence of chemistry researchers from around the globe.