睡眠模式、生活方式和20种癌症的风险：来自英国生物银行队列的研究结果

IF 2.6 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Journal of Public Health Pub Date : 2025-01-17 eCollection Date: 2024-01-01 DOI:10.3389/ijph.2024.1607726

Yue-Ze Zhao, Wen-Li Zhang, Kai-Wen Zhang, Yong-Qiao He, Wen-Qiong Xue, Da-Wei Yang, Hua Diao, Ruo-Wen Xiao, Ying Liao, Qiao-Ling Wang, Wei-Hua Jia, Tong-Min Wang

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引用次数: 0

摘要

目的：睡眠健康和其他生活方式行为在公共卫生中越来越受到关注，特别是在预防癌症方面，但缺乏全面的评估。方法：该研究包括380,042名英国生物银行参与者。健康睡眠评分基于五个睡眠因素：睡眠类型、睡眠持续时间、失眠、打鼾和白天打瞌睡。健康生活方式评分基于四个生活方式因素：吸烟、饮酒、饮食和体育活动。采用Cox比例风险模型检验健康睡眠和生活方式对癌症风险的影响。结果：健康的睡眠和生活方式与降低整体癌症和特定癌症部位的风险显著相关。与不健康睡眠和生活方式的参与者相比，拥有健康睡眠和生活方式的参与者总体患癌症（HR = 0.72, 95% CI = 0.68-0.77）、肝癌（HR = 0.53, 95% CI = 0.31-0.90）、膀胱癌（HR = 0.61, 95% CI = 0.47-0.79）、肺癌（HR = 0.22, 95% CI = 0.19-0.27）和结直肠癌（HR = 0.80, 95% CI = 0.66-0.96）的风险较低。结论：我们的研究结果强调了公共卫生教育和干预措施对改善睡眠和其他生活方式行为预防癌症的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sleep Pattern, Lifestyle Pattern, and Risks of Overall and 20 Types of Cancers: Findings From the UK Biobank Cohort.

Objectives: Sleep health and other lifestyle behaviours are gaining increasing attention in public health, particularly for cancer prevention, but a comprehensive assessment is lacking.

Methods: The study included 380,042 UK Biobank participants. A healthy sleep score was constructed based on five sleep factors: chronotype, sleep duration, insomnia, snoring, and daytime dozing. A healthy lifestyle score was constructed based on four lifestyle factors: smoking, alcohol consumption, diet and physical activity. The effect of healthy sleep and lifestyle on cancer risk was examined by Cox proportional hazard models.

Results: Both healthy sleep and lifestyle patterns were significantly associated with a reduced risk of overall cancer and specific cancer sites. Participants with healthy sleep and lifestyle patterns had a lower risk of overall cancer (HR = 0.72, 95% CI = 0.68-0.77), liver cancer (HR = 0.53, 95% CI = 0.31-0.90), bladder cancer (HR = 0.61, 95% CI = 0.47-0.79), lung cancer (HR = 0.22, 95% CI = 0.19-0.27), and colorectal cancer (HR = 0.80, 95% CI = 0.66-0.96) compared to those with unhealthy patterns.

Conclusion: Our findings highlight the importance of public health education and interventions to improve sleep and other lifestyle behaviours for cancer prevention.

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来源期刊

International Journal of Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

2.20%

发文量

269

审稿时长

12 months

期刊介绍： The International Journal of Public Health publishes scientific articles relevant to global public health, from different countries and cultures, and assembles them into issues that raise awareness and understanding of public health problems and solutions. The Journal welcomes submissions of original research, critical and relevant reviews, methodological papers and manuscripts that emphasize theoretical content. IJPH sometimes publishes commentaries and opinions. Special issues highlight key areas of current research. The Editorial Board''s mission is to provide a thoughtful forum for contemporary issues and challenges in global public health research and practice.