An Uncommon Etiology of Photographic Negative of Pulmonary Edema in an Undifferentiated Connective Tissue Disorder Patient.

The gamut of connective tissue disorders (CTDs) is vast. In addition to involvement of the rheumatological system, other organs like the renal and pulmonary systems are frequently affected in CTDs over the course of illness. The involvement of the pulmonary system commonly includes interstitial lung disease (ILD) and infections, mainly due to immunosuppression. A chest radiograph is the basic investigation done in these patients. Some radiographic patterns have typically been attributed to specific diagnoses and etiologies. Here, we discuss a 40-year-old woman's case with undifferentiated connective tissue disease (UCTD) having a classic imaging picture of a photographic negative of pulmonary edema. However, despite a classic textbook radiographic picture suggesting an inflammatory condition of the lung, a final diagnosis of malignancy was reached on biopsy.