青年人中强度经颅静电磁刺激的时间动态。

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL
Journal of clinical medicine research Pub Date : 2025-01-01 Epub Date: 2024-12-31 DOI:10.14740/jocmr6130
Pan Ling Chen, Xiang Cui, Qi Zhang, Hong Da Zheng, Fan Rong Kong, Hua Ye, Jin Mei Guo, Min Cui
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引用次数: 0

摘要

背景:经颅静磁刺激(tSMS)作为一种新型的无创脑刺激(NIBS)技术正逐渐受到广泛关注。本研究旨在探讨颅磁刺激对健康成人躯体感觉皮层兴奋性的影响。方法:招募40名健康志愿者,随机分为干预组(tSMS)和对照组(sham),每组20人。干预组在C3部位进行180 mT钕磁体刺激30 min,对照组进行非磁性圆柱体假刺激。电极按10-20体系放置在C3和Fz位点。分别在基线、刺激后立即(0 - 2分钟)、5 - 7分钟和10 - 12分钟测量体感诱发电位(sep) N20分量振幅,以评估刺激对皮质兴奋性的影响。结果:静磁刺激30 min后,tSMS组C3部位SEP N20分量振幅平均下降13.2%,刺激后0 ~ 2 min显著下降13.7% (P < 0.001)。这种下降持续到5 - 7分钟,减少了16.6% (P < 0.001),在10 - 12分钟减少到9.3% (P = 0.034)。时间点、组间差异有统计学意义(P = 0.003)。对照组SEP N20成分振幅在整个实验过程中无明显变化(P = 0.382),两组间差异无统计学意义(P = 0.195)。结论:这些结果证实,单次颅磁刺激可以有效地抑制年轻人体感觉皮层的兴奋性。这一发现强调了颅磁刺激作为一种有前途的、无创的脑刺激技术的潜力,具有广泛的应用前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Temporal Dynamics of Moderate-Intensity Transcranial Static Magnetic Stimulation in Young Adults.

Background: Transcranial static magnetic stimulation (tSMS) as a new noninvasive brain stimulation (NIBS) technique is gradually gaining widespread attention. This study aims to investigate the effects of tSMS on the excitability of the somatosensory cortex in healthy adults.

Methods: Forty healthy volunteers were recruited and randomly assigned to either the intervention group (tSMS) or the control group (sham), with 20 participants in each. The intervention group received 30 min of 180 mT neodymium magnet stimulation at the C3 site, while the control group underwent sham stimulation with a non-magnetic cylinder. Electrodes were placed at the C3 and Fz sites according to the 10-20 system. Somatosensory evoked potentials (SEPs) N20 component amplitudes were measured at baseline, immediately after stimulation (0 - 2 min), 5 - 7 min, and 10 - 12 min post-stimulation to evaluate the effects on cortical excitability.

Results: Following 30 min of static magnetic stimulation, the SEP N20 component amplitude at the C3 site in the tSMS group decreased by an average of 13.2%, with a significant reduction of 13.7% within 0 - 2 min post-stimulation (P < 0.001). This decrease persisted at 5 - 7 min, with a reduction of 16.6% (P < 0.001), and diminished to 9.3% at 10 - 12 min (P = 0.034). Significant differences were observed between time points and groups (P = 0.003). In the control group, no significant changes were observed in SEP N20 component amplitude throughout the experiment (P = 0.382), and there was no significant difference between the two groups (P = 0.195).

Conclusions: These results confirm that a single session of tSMS effectively inhibits cortical excitability in the somatosensory cortex of young adults. This finding underscores the potential of tSMS as a promising, noninvasive brain stimulation technique with broad future applications.

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