Ana Carolina Pereira de Godoy, Reinaldo Bugarelli Bestetti
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引用次数: 0
摘要
背景：COVID-19是目前最重要的医疗挑战之一，因为它影响到整个人口，儿童和成年人一样容易受到感染。目的：本研究的目的是评估19岁以下个体与成年人的死亡率。方法：本回顾性观察性研究分析了巴西SP市 o Jose do里约热内卢Preto市de Base医院和母婴医院所有通过实时逆转录聚合酶链反应（RT-PCR）诊断为COVID-19的患者的病历。在8986例住院的COVID-19阳性患者中，19岁以下383例（I组），成人8603例（II组）。结果：II组总死亡率显著高于对照组（p值< 0.0001）(n = 2185；25.4%)，与第一组相比(n = 12；3.13%)。I组12例死亡患者中有11例有相关疾病。1岁以下婴儿死亡人数为2/123(1.63%)，1- 4岁儿童死亡人数为4/95(4.21%)，5- 9岁儿童死亡人数为1/47(2.13%)，10- 14岁青少年死亡人数为1/40(2.50%)，15- 19岁青少年死亡人数为4/78（5.13%）。结论：儿童和青少年的COVID-19死亡率显著低于成人，并与其他合并症相关。临床试验:
Hospitalization and mortality in children due to COVID-19. A retrospective study from Brazil.
Background: Background: COVID-19 is currently one of the most important medical challenges as it affects the entire population, with children being infected as easily as adults.
Objective: The objective of this study was to evaluate the prevalence of mortality in under 19-year-old individuals compared to that of adults.
Methods: This retrospective, observational study analyzed the medical records of all patients diagnosed with COVID-19 by real-time reverse transcription-polymerase chain reaction (RT-PCR) who were hospitalized at Hospital de Base and the Infant and Maternal Hospital of São Jose do Rio Preto, SP, Brazil. Of a total of 8986 hospitalized COVID-19 positive patients, 383 were under 19 years old (Group I) and 8603 were adults (Group II).
Results: Overall mortality was significantly higher (p-value < 0.0001) in Group II (n = 2185; 25.4%) compared to Group I (n = 12; 3.13%). Eleven of the 12 patients of Group I that died had associated diseases. The number of deaths of under 1-year-old infants was 2/123 (1.63%), of 1- to 4-year-old children it was 4/95 (4.21%), of 5- to 9-year-old children it was 1/47 (2.13%), of 10- to 14-year-old adolescents it was 1/40 (2.50%) and of 15- to 19-year-old adolescents it was 4/78 (5.13%).
Conclusions: Mortality from COVID-19 in children and adolescents was significantly lower than in adults and associated with other comorbidities.
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