精神分裂症的表观遗传控制。

Q1 Biochemistry, Genetics and Molecular Biology

Sub-cellular biochemistry Pub Date : 2025-01-01 DOI:10.1007/978-3-031-75980-2_5

Claudio D'Addario, Martina Di Bartolomeo

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引用次数: 0

摘要

精神分裂症是一种严重而复杂的精神疾病，是全世界致残的前15个主要原因之一。尽管公认的遗传因素，遗传和环境风险因素之间的复杂相互作用在精神分裂症和一般精神障碍的发展中起着关键作用。本章涵盖了所有的临床证据，表明如何分析精神分裂症的表观遗传调节可能与理解精神分裂症的发病机制有关，并可能有助于开发新的药物治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epigenetic Control in Schizophrenia.

Schizophrenia is a severe and complex psychiatric condition ranking among the top 15 leading causes of disability worldwide. Despite the well-established heritability component, a complex interplay between genetic and environmental risk factors plays a key role in the development of schizophrenia and psychotic disorders in general. This chapter covers all the clinical evidence showing how the analysis of the epigenetic modulation in schizophrenia might be relevant to understand the pathogenesis of schizophrenia as well as potentially useful to develop new pharmacotherapies.

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来源期刊

Sub-cellular biochemistry Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

5.90

自引率

0.00%

发文量

期刊介绍： The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work.