Vasiliki Margaroni, Pantelis Karaiskos, Andreas Iosif, Anastasios Episkopakis, Efi Koutsouveli, Eleftherios P Pappas
{"title":"1.5T MR-linacs小场剂量测定校正因子研究。","authors":"Vasiliki Margaroni, Pantelis Karaiskos, Andreas Iosif, Anastasios Episkopakis, Efi Koutsouveli, Eleftherios P Pappas","doi":"10.1088/1361-6560/ada682","DOIUrl":null,"url":null,"abstract":"<p><p><i>Objective</i>. Clinical dosimetry in the presence of a 1.5 T magnetic field is challenging, let alone in case small fields are involved. The scope of this study is to determine a set of relevant correction factors for a variety of MR-compatible detectors with emphasis on small fields. Two dosimetry formalisms adopted from the literature are considered.<i>Approach</i>. Six small-cavity ionization chambers (from three manufacturers), four active solid-state detectors and a thermoluminescence dosimeter microcube were modeled in the EGSnrc Monte Carlo code. Phase space files for field sizes down to 1 × 1 cm<sup>2</sup>of the Unity 1.5 T/7 MV MR-linac (Elekta, UK) were used as source models. Simulations were performed to calculate thekQB,QfB,f(also known askB,Q),kQmsrB,fmsrandkQclin,QmsrB,fclin,fmsrrelevant to two different dosimetry formalisms. Two detector orientations with respect to the magnetic field were considered. Moreover, the effect of the ionization chamber's stem length (a construction parameter) on the correction factor was investigated. Simulations were also carried out to determine whether correction factors obtained in water can be applied in dosimetry procedures involving water-equivalent solid phantoms.<i>Main results</i>. Under thekQB,QfB,f-based formalism, the required corrections to ionization chamber responses did not exceed 1.5% even for the smallest field size considered. A much wider range ofkQB,QfB,fvalues was obtained for the active solid-state detectors included in the simulations. This is the first study to reportkQclin,QmsrB,fclin,fmsrvalues for ionization chambers. The impact of the stem on correction factors is not significant for lengths ⩾0.75 cm. Correction factors determined in water are also valid in dosimetry protocols employing solid phantoms.<i>Significance</i>. This work substantially expands the range of available detectors that can be used in small field dosimetry, enabling more options for commissioning, beam modeling and quality assurance procedures in 1.5 T MR-Linacs. However, more studies are needed to establish a complete and reliable dataset.</p>","PeriodicalId":20185,"journal":{"name":"Physics in medicine and biology","volume":"70 2","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"On the correction factors for small field dosimetry in 1.5T MR-linacs.\",\"authors\":\"Vasiliki Margaroni, Pantelis Karaiskos, Andreas Iosif, Anastasios Episkopakis, Efi Koutsouveli, Eleftherios P Pappas\",\"doi\":\"10.1088/1361-6560/ada682\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Objective</i>. Clinical dosimetry in the presence of a 1.5 T magnetic field is challenging, let alone in case small fields are involved. The scope of this study is to determine a set of relevant correction factors for a variety of MR-compatible detectors with emphasis on small fields. Two dosimetry formalisms adopted from the literature are considered.<i>Approach</i>. Six small-cavity ionization chambers (from three manufacturers), four active solid-state detectors and a thermoluminescence dosimeter microcube were modeled in the EGSnrc Monte Carlo code. Phase space files for field sizes down to 1 × 1 cm<sup>2</sup>of the Unity 1.5 T/7 MV MR-linac (Elekta, UK) were used as source models. Simulations were performed to calculate thekQB,QfB,f(also known askB,Q),kQmsrB,fmsrandkQclin,QmsrB,fclin,fmsrrelevant to two different dosimetry formalisms. Two detector orientations with respect to the magnetic field were considered. Moreover, the effect of the ionization chamber's stem length (a construction parameter) on the correction factor was investigated. Simulations were also carried out to determine whether correction factors obtained in water can be applied in dosimetry procedures involving water-equivalent solid phantoms.<i>Main results</i>. Under thekQB,QfB,f-based formalism, the required corrections to ionization chamber responses did not exceed 1.5% even for the smallest field size considered. A much wider range ofkQB,QfB,fvalues was obtained for the active solid-state detectors included in the simulations. This is the first study to reportkQclin,QmsrB,fclin,fmsrvalues for ionization chambers. The impact of the stem on correction factors is not significant for lengths ⩾0.75 cm. Correction factors determined in water are also valid in dosimetry protocols employing solid phantoms.<i>Significance</i>. This work substantially expands the range of available detectors that can be used in small field dosimetry, enabling more options for commissioning, beam modeling and quality assurance procedures in 1.5 T MR-Linacs. 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On the correction factors for small field dosimetry in 1.5T MR-linacs.
Objective. Clinical dosimetry in the presence of a 1.5 T magnetic field is challenging, let alone in case small fields are involved. The scope of this study is to determine a set of relevant correction factors for a variety of MR-compatible detectors with emphasis on small fields. Two dosimetry formalisms adopted from the literature are considered.Approach. Six small-cavity ionization chambers (from three manufacturers), four active solid-state detectors and a thermoluminescence dosimeter microcube were modeled in the EGSnrc Monte Carlo code. Phase space files for field sizes down to 1 × 1 cm2of the Unity 1.5 T/7 MV MR-linac (Elekta, UK) were used as source models. Simulations were performed to calculate thekQB,QfB,f(also known askB,Q),kQmsrB,fmsrandkQclin,QmsrB,fclin,fmsrrelevant to two different dosimetry formalisms. Two detector orientations with respect to the magnetic field were considered. Moreover, the effect of the ionization chamber's stem length (a construction parameter) on the correction factor was investigated. Simulations were also carried out to determine whether correction factors obtained in water can be applied in dosimetry procedures involving water-equivalent solid phantoms.Main results. Under thekQB,QfB,f-based formalism, the required corrections to ionization chamber responses did not exceed 1.5% even for the smallest field size considered. A much wider range ofkQB,QfB,fvalues was obtained for the active solid-state detectors included in the simulations. This is the first study to reportkQclin,QmsrB,fclin,fmsrvalues for ionization chambers. The impact of the stem on correction factors is not significant for lengths ⩾0.75 cm. Correction factors determined in water are also valid in dosimetry protocols employing solid phantoms.Significance. This work substantially expands the range of available detectors that can be used in small field dosimetry, enabling more options for commissioning, beam modeling and quality assurance procedures in 1.5 T MR-Linacs. However, more studies are needed to establish a complete and reliable dataset.
期刊介绍:
The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry