卵巢癌的临床病理和分子特征及对2014年FIGO分期的评论

IF 4.5 1区医学 Q1 PATHOLOGY

American Journal of Surgical Pathology Pub Date : 2025-01-14 DOI:10.1097/PAS.0000000000002352

Jaime Prat, Emanuela D'Angelo, Iñigo Espinosa

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引用次数: 0

摘要

根据组织病理学和分子遗传学，卵巢癌有5种主要亚型：高级别浆液性（70%）、子宫内膜样（10%）、透明细胞性（10%）、黏液性（3% ~ 4%）和低级别浆液性(

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Ovarian Carcinomas: Clinicopathologic and Molecular Features With Comments on 2014 FIGO Staging.

According to histopathology and molecular genetics, there are 5 major subtypes of ovarian carcinomas: high-grade serous (70%), endometrioid (10%), clear cell (10%), mucinous (3% to 4%), and low-grade serous (<5%) carcinomas. These tumors, which constitute over 95% of cases, represent distinct diseases with different prognoses and therapy. This review outlines contemporary advances in molecular pathology, which have expanded our knowledge of the biology of epithelial ovarian cancer and are also important to patient management. We also comment on some controversial points of the FIGO staging classification that we proposed in 2014.

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来源期刊

American Journal of Surgical Pathology 医学-病理学

CiteScore

10.30

自引率

5.40%

发文量

295

审稿时长

1 months

期刊介绍： The American Journal of Surgical Pathology has achieved worldwide recognition for its outstanding coverage of the state of the art in human surgical pathology. In each monthly issue, experts present original articles, review articles, detailed case reports, and special features, enhanced by superb illustrations. Coverage encompasses technical methods, diagnostic aids, and frozen-section diagnosis, in addition to detailed pathologic studies of a wide range of disease entities. Official Journal of The Arthur Purdy Stout Society of Surgical Pathologists and The Gastrointestinal Pathology Society.