Rahul Ghosh, Jacob Bahnmiller, Andrew Warren, Elina Quiroga, Niten Singh, Benjamin W Starnes, Sara L Zettervall, Kirsten D Dansey
{"title":"邻近和先前医疗接触影响腹主动脉瘤破裂后随访。","authors":"Rahul Ghosh, Jacob Bahnmiller, Andrew Warren, Elina Quiroga, Niten Singh, Benjamin W Starnes, Sara L Zettervall, Kirsten D Dansey","doi":"10.1016/j.jvs.2024.12.130","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Post-repair surveillance of ruptured abdominal aortic aneurysm (rAAA) is critical for detecting potential complications. Substantial loss to follow-up has been reported in populations undergoing elective endovascular aortic repair (EVAR); however, there is limited data on follow-up rate among patients presenting with rupture. Thus, we investigated follow-up trends and factors influencing retention at a major academic referral center with a wide service area.</p><p><strong>Methods: </strong>We included patients with rAAA from 2002-2023 in this retrospective study. Loss to follow-up was defined as absence of vascular surgeon evaluation for 2 years (EVAR) or 5 years (open repair) prior to death or present day. Multivariate regression and survival models assessed the influence of potential factors on follow-up and survival outcomes.</p><p><strong>Results: </strong>Of 455 patients who presented with rAAA, 60% who underwent EVAR and 39% who underwent open repair were lost to follow-up. 20% of patients who underwent EVAR were lost after initial admission and 40% of patients were lost after the 1-month post-operative follow-up visit. There were no significant differences in baseline demographics. Patients lost to follow-up less commonly had Stage 4 CKD (7.2% vs. 24.3%, p = 0.02) and prior EVAR (10.0% vs 29.2%, p=0.01) at time of rupture. Secondary interventions were less common in patients lost to follow-up (14.5% vs 39.0%, p=0.01). In multivariate analysis of patients who underwent an EVAR, residing more than 10 miles from hospital was associated with loss to follow-up (OR:4.93 [1.14-21.29]). Prior endograft at time of rupture (OR:0.24 [0.06-0.89]), and eGFR < 30 (OR:0.23 [0.06-0.93]) were associated with complete follow-up in patients who underwent EVAR. Patients who were lost to follow up trended towards worse survival (HR 2.04 [0.67-6.26]), while prior endograft was associated with significantly worse survival after EVAR (HR 3.11 [1.20 - 8.04]).</p><p><strong>Conclusions: </strong>Although most patients with rAAA attend their 1-month post-operative visit, the majority are subsequently lost to follow-up. Geographic proximity to the hospital and higher baseline medical engagement, as indicated by prior endograft and chronic kidney disease, appeared to be protective against such loss. Targeted counseling and engagement at the 1-month post-operative visit, particularly in patients with less comorbid conditions, may enhance retention to long-term follow-up.</p>","PeriodicalId":17475,"journal":{"name":"Journal of Vascular Surgery","volume":" ","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Proximity and Prior Medical Engagement Influence Follow-Up After Ruptured Abdominal Aortic Aneurysm.\",\"authors\":\"Rahul Ghosh, Jacob Bahnmiller, Andrew Warren, Elina Quiroga, Niten Singh, Benjamin W Starnes, Sara L Zettervall, Kirsten D Dansey\",\"doi\":\"10.1016/j.jvs.2024.12.130\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Post-repair surveillance of ruptured abdominal aortic aneurysm (rAAA) is critical for detecting potential complications. Substantial loss to follow-up has been reported in populations undergoing elective endovascular aortic repair (EVAR); however, there is limited data on follow-up rate among patients presenting with rupture. Thus, we investigated follow-up trends and factors influencing retention at a major academic referral center with a wide service area.</p><p><strong>Methods: </strong>We included patients with rAAA from 2002-2023 in this retrospective study. Loss to follow-up was defined as absence of vascular surgeon evaluation for 2 years (EVAR) or 5 years (open repair) prior to death or present day. Multivariate regression and survival models assessed the influence of potential factors on follow-up and survival outcomes.</p><p><strong>Results: </strong>Of 455 patients who presented with rAAA, 60% who underwent EVAR and 39% who underwent open repair were lost to follow-up. 20% of patients who underwent EVAR were lost after initial admission and 40% of patients were lost after the 1-month post-operative follow-up visit. There were no significant differences in baseline demographics. Patients lost to follow-up less commonly had Stage 4 CKD (7.2% vs. 24.3%, p = 0.02) and prior EVAR (10.0% vs 29.2%, p=0.01) at time of rupture. Secondary interventions were less common in patients lost to follow-up (14.5% vs 39.0%, p=0.01). In multivariate analysis of patients who underwent an EVAR, residing more than 10 miles from hospital was associated with loss to follow-up (OR:4.93 [1.14-21.29]). Prior endograft at time of rupture (OR:0.24 [0.06-0.89]), and eGFR < 30 (OR:0.23 [0.06-0.93]) were associated with complete follow-up in patients who underwent EVAR. Patients who were lost to follow up trended towards worse survival (HR 2.04 [0.67-6.26]), while prior endograft was associated with significantly worse survival after EVAR (HR 3.11 [1.20 - 8.04]).</p><p><strong>Conclusions: </strong>Although most patients with rAAA attend their 1-month post-operative visit, the majority are subsequently lost to follow-up. Geographic proximity to the hospital and higher baseline medical engagement, as indicated by prior endograft and chronic kidney disease, appeared to be protective against such loss. Targeted counseling and engagement at the 1-month post-operative visit, particularly in patients with less comorbid conditions, may enhance retention to long-term follow-up.</p>\",\"PeriodicalId\":17475,\"journal\":{\"name\":\"Journal of Vascular Surgery\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-01-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Vascular Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jvs.2024.12.130\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jvs.2024.12.130","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
摘要
目的:腹主动脉瘤破裂(rAAA)术后监测是发现潜在并发症的关键。在接受选择性血管内主动脉修复(EVAR)的人群中,有大量随访损失的报道;然而,关于破裂患者随访率的数据有限。因此,我们调查了一个具有广泛服务区域的主要学术转诊中心的后续趋势和影响保留率的因素。方法:回顾性研究纳入2002-2023年rAAA患者。随访缺失被定义为在死亡前或现在2年(EVAR)或5年(开放式修复)内没有血管外科医生评估。多变量回归和生存模型评估了潜在因素对随访和生存结果的影响。结果:在455例出现rAAA的患者中,60%的患者接受了EVAR, 39%的患者接受了开放式修复,未能随访。20%的EVAR患者在初次入院后丢失,40%的患者在术后1个月随访后丢失。在基线人口统计学上没有显著差异。失去随访的患者在破裂时较少发生4期CKD (7.2% vs 24.3%, p= 0.02)和既往EVAR (10.0% vs 29.2%, p=0.01)。失访患者的二次干预较少(14.5% vs 39.0%, p=0.01)。在对接受EVAR的患者的多变量分析中,居住在距离医院超过10英里的地方与随访损失相关(OR:4.93[1.14-21.29])。在EVAR患者中,在破裂时进行过内移植物移植(OR:0.24[0.06-0.89])和eGFR < 30 (OR:0.23[0.06-0.93])与完全随访相关。未随访的患者生存率较差(HR 2.04[0.67-6.26]),而先前的内移植与EVAR后生存率显著较差相关(HR 3.11[1.20 - 8.04])。结论:虽然大多数rAAA患者术后1个月都有随访,但大多数患者随后失去了随访。地理位置靠近医院和较高的基线医疗参与,如既往的内移植物和慢性肾脏疾病所表明的,似乎可以防止这种损失。在术后1个月的随访中进行针对性的咨询和参与,特别是在合并症较少的患者中,可以提高长期随访的保留率。
Proximity and Prior Medical Engagement Influence Follow-Up After Ruptured Abdominal Aortic Aneurysm.
Objective: Post-repair surveillance of ruptured abdominal aortic aneurysm (rAAA) is critical for detecting potential complications. Substantial loss to follow-up has been reported in populations undergoing elective endovascular aortic repair (EVAR); however, there is limited data on follow-up rate among patients presenting with rupture. Thus, we investigated follow-up trends and factors influencing retention at a major academic referral center with a wide service area.
Methods: We included patients with rAAA from 2002-2023 in this retrospective study. Loss to follow-up was defined as absence of vascular surgeon evaluation for 2 years (EVAR) or 5 years (open repair) prior to death or present day. Multivariate regression and survival models assessed the influence of potential factors on follow-up and survival outcomes.
Results: Of 455 patients who presented with rAAA, 60% who underwent EVAR and 39% who underwent open repair were lost to follow-up. 20% of patients who underwent EVAR were lost after initial admission and 40% of patients were lost after the 1-month post-operative follow-up visit. There were no significant differences in baseline demographics. Patients lost to follow-up less commonly had Stage 4 CKD (7.2% vs. 24.3%, p = 0.02) and prior EVAR (10.0% vs 29.2%, p=0.01) at time of rupture. Secondary interventions were less common in patients lost to follow-up (14.5% vs 39.0%, p=0.01). In multivariate analysis of patients who underwent an EVAR, residing more than 10 miles from hospital was associated with loss to follow-up (OR:4.93 [1.14-21.29]). Prior endograft at time of rupture (OR:0.24 [0.06-0.89]), and eGFR < 30 (OR:0.23 [0.06-0.93]) were associated with complete follow-up in patients who underwent EVAR. Patients who were lost to follow up trended towards worse survival (HR 2.04 [0.67-6.26]), while prior endograft was associated with significantly worse survival after EVAR (HR 3.11 [1.20 - 8.04]).
Conclusions: Although most patients with rAAA attend their 1-month post-operative visit, the majority are subsequently lost to follow-up. Geographic proximity to the hospital and higher baseline medical engagement, as indicated by prior endograft and chronic kidney disease, appeared to be protective against such loss. Targeted counseling and engagement at the 1-month post-operative visit, particularly in patients with less comorbid conditions, may enhance retention to long-term follow-up.
期刊介绍:
Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.