Beatriz Estalayo-Gutiérrez, María José Álvarez Pasquín, Francisco Germain
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They were evaluated with the Goldberg and Hamilton tests and classified into the Emotional Well-Being group (EWB, <i>n</i> = 86) or the Anxiety and/or Depression group (AD, <i>n</i> = 147). Just half of each group received an AI.</p><p><strong>Intervention: </strong>Listening to classical music processed through a frequency modulator (Earducator) to attenuate abnormal frequencies, 30 min per session, two sessions a day for 5 days.</p><p><strong>Main measurements: </strong>Hamilton Tests for Anxiety and Hamilton Test for Depression, at 3 and 6 months. <b>Results</b>: In the analysis by protocol, EWB with AI (<i>n</i> = 14) obtained lower scores in anxiety and depression at 3 and 6 months than EWB without AI (<i>n</i> = 36) (<i>p</i> < 0.05), the effects being large and moderate, respectively; AD with AI (<i>n</i> = 31) had lower scores on anxiety and depression at 3 months and anxiety at 6 months than AD without AI (<i>n</i> = 52) (<i>p</i> < 0.05), the effect being small. No damage reported. <b>Conclusions</b>: The AI \"Bérard in 10\" significantly prevents the onset of anxiety and depression and somewhat improves the effect of standard treatments in primary care.</p>","PeriodicalId":15533,"journal":{"name":"Journal of Clinical Medicine","volume":"14 1","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11721829/pdf/","citationCount":"0","resultStr":"{\"title\":\"Approach to Mental Health Through a Frequency Modulated Auditory Intervention: A Controlled and Randomized Clinical Trial.\",\"authors\":\"Beatriz Estalayo-Gutiérrez, María José Álvarez Pasquín, Francisco Germain\",\"doi\":\"10.3390/jcm14010288\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objective</b>: The clinical trial Effect of Modulated Auditory Stimulation on Interaural Auditory Perception (NCT0544189) aimed to determine whether an auditory intervention (AI)-\\\"Bérard in 10\\\"-can enhance the effect of standard therapies for people with anxiety and/or depression. <b>Methods</b>: Design: unblinded, randomized, controlled clinical trial.</p><p><strong>Location: </strong>Mejorada del Campo Health Centre, Madrid (Primary Care).</p><p><strong>Participants: </strong>A total of 233 patients selected by systematic sampling and meeting the following selection criteria: age of majority, absence of severe acute pathology or chronic decompensated pathology. They were evaluated with the Goldberg and Hamilton tests and classified into the Emotional Well-Being group (EWB, <i>n</i> = 86) or the Anxiety and/or Depression group (AD, <i>n</i> = 147). Just half of each group received an AI.</p><p><strong>Intervention: </strong>Listening to classical music processed through a frequency modulator (Earducator) to attenuate abnormal frequencies, 30 min per session, two sessions a day for 5 days.</p><p><strong>Main measurements: </strong>Hamilton Tests for Anxiety and Hamilton Test for Depression, at 3 and 6 months. <b>Results</b>: In the analysis by protocol, EWB with AI (<i>n</i> = 14) obtained lower scores in anxiety and depression at 3 and 6 months than EWB without AI (<i>n</i> = 36) (<i>p</i> < 0.05), the effects being large and moderate, respectively; AD with AI (<i>n</i> = 31) had lower scores on anxiety and depression at 3 months and anxiety at 6 months than AD without AI (<i>n</i> = 52) (<i>p</i> < 0.05), the effect being small. 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引用次数: 0
摘要
目的:调节听觉刺激对耳间听觉感知的影响(NCT0544189)的临床试验旨在确定听觉干预(AI)-“bsamrard in 10”-是否可以增强标准治疗对焦虑和/或抑郁症患者的效果。方法:设计:非盲、随机、对照临床试验。地点:马德里Mejorada del Campo保健中心(初级保健)。参与者:通过系统抽样选择的患者共233例,符合以下选择标准:年龄较大,无严重急性病理或慢性失代偿病理。他们用Goldberg和Hamilton测试进行评估,并被分为情绪健康组(EWB, n = 86)或焦虑和/或抑郁组(AD, n = 147)。每组中只有一半的人获得了人工智能。干预:听经调频器(Earducator)处理过的古典音乐,以衰减异常频率,每次30分钟,每天两次,持续5天。主要测量:汉密尔顿焦虑测试和汉密尔顿抑郁测试,在3个月和6个月。结果:在方案分析中,有人工智能的EWB (n = 14)在第3个月和第6个月的焦虑和抑郁评分低于没有人工智能的EWB (n = 36) (p < 0.05),效果分别为大、中;合并AI的AD患者(n = 31)在3个月和6个月时的焦虑和抑郁评分均低于未合并AI的AD患者(n = 52) (p < 0.05),但影响较小。没有损失报告。结论:人工智能“10年抑郁量表”可显著预防焦虑和抑郁的发生,并在一定程度上提高了初级保健标准治疗的效果。
Approach to Mental Health Through a Frequency Modulated Auditory Intervention: A Controlled and Randomized Clinical Trial.
Objective: The clinical trial Effect of Modulated Auditory Stimulation on Interaural Auditory Perception (NCT0544189) aimed to determine whether an auditory intervention (AI)-"Bérard in 10"-can enhance the effect of standard therapies for people with anxiety and/or depression. Methods: Design: unblinded, randomized, controlled clinical trial.
Location: Mejorada del Campo Health Centre, Madrid (Primary Care).
Participants: A total of 233 patients selected by systematic sampling and meeting the following selection criteria: age of majority, absence of severe acute pathology or chronic decompensated pathology. They were evaluated with the Goldberg and Hamilton tests and classified into the Emotional Well-Being group (EWB, n = 86) or the Anxiety and/or Depression group (AD, n = 147). Just half of each group received an AI.
Intervention: Listening to classical music processed through a frequency modulator (Earducator) to attenuate abnormal frequencies, 30 min per session, two sessions a day for 5 days.
Main measurements: Hamilton Tests for Anxiety and Hamilton Test for Depression, at 3 and 6 months. Results: In the analysis by protocol, EWB with AI (n = 14) obtained lower scores in anxiety and depression at 3 and 6 months than EWB without AI (n = 36) (p < 0.05), the effects being large and moderate, respectively; AD with AI (n = 31) had lower scores on anxiety and depression at 3 months and anxiety at 6 months than AD without AI (n = 52) (p < 0.05), the effect being small. No damage reported. Conclusions: The AI "Bérard in 10" significantly prevents the onset of anxiety and depression and somewhat improves the effect of standard treatments in primary care.
期刊介绍:
Journal of Clinical Medicine (ISSN 2077-0383), is an international scientific open access journal, providing a platform for advances in health care/clinical practices, the study of direct observation of patients and general medical research. This multi-disciplinary journal is aimed at a wide audience of medical researchers and healthcare professionals.
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