Abel Dambrain, Charles Boursot, Kévin Cohen Tannugi, Julien Reichart, Franck Lacoeuille
{"title":"病例报告：脑[18F]FDG PET/CT在Sydenham舞蹈病诊断中的应用。","authors":"Abel Dambrain, Charles Boursot, Kévin Cohen Tannugi, Julien Reichart, Franck Lacoeuille","doi":"10.3389/fnume.2024.1527150","DOIUrl":null,"url":null,"abstract":"<p><p>Sydenham's chorea is an autoimmune reaction against cerebral basal ganglia associated with rheumatic fever, caused by group A beta-hemolytic streptococcus infection. Diagnosis of this condition is difficult because of significant delay between infection onset and symptoms presentation, resulting in few positive biological tests or imaging exams. We report the case of a nine-year-old boy exhibiting hemicorporal abnormal movements with tics for whom [<sup>18</sup>F]FDG PET/CT exam allowed to make the diagnosis, associated with anti-DNase B elevation. Other biology, spinal tap, EEG and imaging modality like MRI or scanner, were non-contributory.</p>","PeriodicalId":73095,"journal":{"name":"Frontiers in nuclear medicine (Lausanne, Switzerland)","volume":"4 ","pages":"1527150"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11703979/pdf/","citationCount":"0","resultStr":"{\"title\":\"Case Report: Utility of brain [<sup>18</sup>F]FDG PET/CT in the diagnosis of Sydenham's chorea.\",\"authors\":\"Abel Dambrain, Charles Boursot, Kévin Cohen Tannugi, Julien Reichart, Franck Lacoeuille\",\"doi\":\"10.3389/fnume.2024.1527150\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Sydenham's chorea is an autoimmune reaction against cerebral basal ganglia associated with rheumatic fever, caused by group A beta-hemolytic streptococcus infection. Diagnosis of this condition is difficult because of significant delay between infection onset and symptoms presentation, resulting in few positive biological tests or imaging exams. We report the case of a nine-year-old boy exhibiting hemicorporal abnormal movements with tics for whom [<sup>18</sup>F]FDG PET/CT exam allowed to make the diagnosis, associated with anti-DNase B elevation. Other biology, spinal tap, EEG and imaging modality like MRI or scanner, were non-contributory.</p>\",\"PeriodicalId\":73095,\"journal\":{\"name\":\"Frontiers in nuclear medicine (Lausanne, Switzerland)\",\"volume\":\"4 \",\"pages\":\"1527150\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11703979/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in nuclear medicine (Lausanne, Switzerland)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3389/fnume.2024.1527150\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in nuclear medicine (Lausanne, Switzerland)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fnume.2024.1527150","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Case Report: Utility of brain [18F]FDG PET/CT in the diagnosis of Sydenham's chorea.
Sydenham's chorea is an autoimmune reaction against cerebral basal ganglia associated with rheumatic fever, caused by group A beta-hemolytic streptococcus infection. Diagnosis of this condition is difficult because of significant delay between infection onset and symptoms presentation, resulting in few positive biological tests or imaging exams. We report the case of a nine-year-old boy exhibiting hemicorporal abnormal movements with tics for whom [18F]FDG PET/CT exam allowed to make the diagnosis, associated with anti-DNase B elevation. Other biology, spinal tap, EEG and imaging modality like MRI or scanner, were non-contributory.
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