Xiaoyun Song, Yue Song, Junjie Gu, Mei Zhang, Lei Zhang, Xiaonan Zheng, Lin Guo, Xiaoting Liu
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引用次数: 0
摘要
在2022-2023年共收集了76份玉米及其制品样品，以估计大连地区伏马菌素（FBs）的膳食暴露情况。采用超高效液相色谱-质谱联用技术（UPLC-MS/MS）对FBs进行鉴定。FB1、FB2、FB3、FB1 + FB2 + FB3的发生率分别为89.5%、77.6%、61.8%和61.8%，平均浓度为140 ~ 1332 μg/kg。在考虑平均水平时，没有发现由于饮食暴露于FBs而导致的个人和累积健康风险。然而，确定性分析显示，儿童和青少年第95次和第99次接触FB1 + FB2 + FB3估计为2.18至3.46 μg kg bw-1day-1，超过了临时最大可耐受日摄入量（PMTDI） 2 μg kg bw-1day-1。概率分析显示，各年龄组第99次暴露量为2.06 ~ 3.08 μg kg bw-1day-1，均超过PMTDI。为了降低大连地区的膳食暴露和健康风险，需要建立最大限量和系统监测。
Fumonisins in maize and its products from Dalian region, China, and risk assessment by deterministic and probabilistic approaches.
A total of 76 samples of maize and its products were collected in 2022-2023 to estimate dietary exposure of fumonisins (FBs) in Dalian region, China. The identification of FBs was performed by ultrahigh performance liquid chromatography coupled with mass spectrometry (UPLC-MS/MS). The occurrences of FB1, FB2, FB3, FB1 + FB2 + FB3 were 89.5%, 77.6%, 61.8%, and 61.8%, respectively, with mean concentrations ranging from 140 to 1332 μg/kg. No individual and cumulative health risks were found due to FBs dietary exposure, when considering the mean level. However, a deterministic analysis showed 95th and 99th exposures of FB1 + FB2 + FB3 for children and adolescents were estimated to be 2.18 to 3.46 μg kg bw-1day-1, exceeding the Provisional Maximum Tolerable Daily Intake (PMTDI) of 2 μg kg bw-1day-1. Probabilistic analysis showed the 99th exposures for all age groups were 2.06 to 3.08 μg kg bw-1day-1, exceeding the PMTDI. Establishment of MLs and systematic monitoring are needed to lower FBs dietary exposure and health risk in the Dalian region.
期刊介绍：
Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling.
Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment.
The scope is initially restricted to:
Additives - food colours, artificial sweeteners, and preservatives;
Residues – veterinary drug and pesticide residues;
Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging.
Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet.
Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.
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