光催化硝基转移反应中乙酸苯乙酯的分子间胺化反应

Organic chemistry frontiers : an international journal of organic chemistry Pub Date : 2025-01-08 DOI:10.1039/d4qo02194k

Yujing Guo , Yifan Guo , Luyao Ding , Linlin Shi , Xinqi Hao , Rene M. Koenigs

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引用次数: 0

摘要

在本研究中，我们通过光催化硝基转移反应报道了1,3-二羰基化合物的C-H功能化。广泛的1,3-二羰基底物和碘类与反应条件相适应，可以直接产生C-H功能化产物，而不需要预先形成亲核烯酸酯等价物。此外，还进行了一系列综合应用和控制实验，从而进一步扩展了该方法的实际应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Intermolecular amination of ethyl benzo ylacetate via photocatalytic nitrene transfer reactions†

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Intermolecular amination of ethyl benzo ylacetate via photocatalytic nitrene transfer reactions†

In this study, we report on a C–H functionalization of 1,3-dicarbonyl compounds via a photocatalytic nitrene transfer reaction. A wide range of 1,3-dicarbonyl substrates and iodinanes were found compatible with the reaction conditions to directly afford the C–H functionalization products without the need of preformation of nucleophilic enolate equivalents. Additionally, a comprehensive series of synthetic applications and control experiments were conducted, thereby further extending the practical utility of this approach.

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来源期刊

Organic chemistry frontiers : an international journal of organic chemistry

CiteScore

7.80

自引率

0.00%

发文量