肥胖儿童legg - calv - perthes病的诊断和治疗。

Lauren Beckish, Madison Ging, Maria Mosman, Cody Kelley, Landree Wilkin, Olivia Wills, Madison Adams, Cassidy Pinion, Cheyenne Bilica, Alavia Anderson, Margaret Sims, Michael Beckish, Deanna M Schmitt
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引用次数: 0

摘要

legg - calv - perthes病(LCPD)是一种以股骨近端血流暂时中断为特征的疾病,常见于15岁及以下儿童。该病的病因通常是特发性的,涉及股骨头缺血性坏死的发展,随后导致骨弱化和畸形。肥胖加重LCPD,与延迟诊断、疾病严重程度增加和双侧受累相关。肥胖个体的瘦素、生长激素和其他炎症介质的改变有助于发病机制。治疗范围从保守措施到手术,对肥胖患者尤其具有挑战性。更好地了解肥胖对慢性阻塞性肺病进展的影响对于量身定制的管理和最佳结果至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosis and Management of Legg-Calvé-Perthes Disease in the Obese Pediatric Population.

Legg-Calvé-Perthes Disease (LCPD) is a condition marked by temporary blood flow disruption to the proximal femur, commonly afflicting children aged 15 and younger. The etiology of the disease is often idiopathic and involves the development of avascular necrosis of the femoral head, subsequently leading to bone weakening and deformity. Obesity exacerbates LCPD, correlating with delayed diagnosis, increased disease severity, and bilateral involvement. Leptin, growth hormone, and other inflammatory mediator alterations in obese individuals contribute to the pathogenesis. Treatment ranges from conservative measures to surgery, with particular challenges in obese patients. An improved understanding of the impact of obesity on LCPD progression is crucial for tailored management and optimal outcomes.

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