Skinmed Pub Date : 2024-12-31 eCollection Date: 2024-01-01
Leah A Goldberg, Sylvia Hsu
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引用次数: 0

摘要

一位二十多岁的白人女性,在过去的6个月里,手上有无症状的丘疹,被风湿病学推荐进行皮肤活检。病人因关节痛向风湿病学家求诊。查体时,手指背侧可见多发暗红色2-5毫米丘疹,多见于足跖周围。粘膜及皮肤其他部位未见丘疹或结节。考虑到沿趾周区域出现特征性的“珊瑚珠”,临床诊断为多中心网状组织细胞增多症(MRH)。4毫米穿刺活检显示组织细胞具有嗜酸性、均匀和细颗粒的“磨砂玻璃”细胞质。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multicentric Reticulohistiocytosis.

A Caucasian woman in her twenties having asymptomatic papules on the hands for the past 6 months was referred by rheumatology for a skin biopsy. The patient had presented to rheumatologist for arthralgia. On physical examination, multiple, dull red, 2-5-mm papules were observed on her dorsal fingers, with most in the periungual regions. No papules or nodules were discovered on the mucosal membranes or other areas of her skin. Given the presence of characteristic "coral beads" along the periungual regions, the clinical diagnosis of multicentric reticulohistiocytosis (MRH) was rendered. A 4-mm punch biopsy revealed histiocytes with eosinophilic, homogenous, and finely granular "ground glass" cytoplasm.

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