慢性疼痛治疗中加巴喷丁类药物的处方模式:单一机构回顾性病历审查

Psychopharmacology bulletin Pub Date : 2025-01-01
Richard T Tran, Anand S Patil, Parker P Nguyen, Grace H Nguyen, Amad Qadeer, Grant H Chen, Ranganathan Govindaraj, Jamal Hasoon
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引用次数: 0

摘要

加巴喷丁和普瑞巴林被广泛用于神经性疼痛的治疗,尽管它们的处方模式、有效性和安全性仍然是正在进行的研究的主题。本回顾性图表分析了从2023年5月1日至2024年4月30日一年间加巴喷丁类药物在慢性疼痛诊所的使用情况。该研究检查了四位疼痛管理医生的患者记录,重点关注那些开加巴喷丁或普瑞巴林的患者。在2395例患者中,478例(19.96%)使用加巴喷丁,236例(9.85%)使用普瑞巴林。加巴喷丁类药物在慢性疼痛治疗中发挥了重要作用,714例(29.81%)患者接受了这两种药物的治疗。研究发现加巴喷丁比普瑞巴林更常被开处方。虽然这两种药物对神经性疼痛都有效,但它们的使用会带来明显的副作用,包括头晕、嗜睡,在某些情况下,还会增加自杀念头的风险。这篇综述强调了在开加巴喷丁类药物时仔细监测患者和个性化治疗方法的重要性。未来跨多个地点的研究和进一步的患者人口统计学分层将加强对加巴喷丁类在临床实践中使用的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prescribing Patterns of Gabapentinoids in Chronic Pain Management: A Single Institution Retrospective Chart Review.

Gabapentin and pregabalin are widely used in the management of neuropathic pain though their prescribing patterns, effectiveness, and safety profiles remain topics of ongoing research. This retrospective chart review analyzed the prevalence of gabapentinoid use in a chronic pain clinic over a one-year period from May 1, 2023, to April 30, 2024. The study examined patient records from four pain management physicians, focusing on those prescribed gabapentin or pregabalin. Of the 2,395 patients reviewed, 478 (19.96%) were prescribed gabapentin, while 236 (9.85%) received pregabalin. Combined, 714 patients (29.81%) were managed with either medication, highlighting the significant role gabapentinoids play in chronic pain treatment. The study found that gabapentin was prescribed more frequently than pregabalin. Although both medications are effective for neuropathic pain, their use comes with notable side effects, including dizziness, somnolence, and, in some cases, an increased risk of suicidal ideation. This review underscores the importance of careful patient monitoring and individualized treatment approaches when prescribing gabapentinoids. Future research across multiple sites and further stratification of patient demographics would enhance understanding of gabapentinoid use in clinical practice.

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