头孢曲松预测肠杆菌分离株对口服高代头孢菌素的敏感性有多准确？

IF 4.1 2区医学 Q2 MICROBIOLOGY

Antimicrobial Agents and Chemotherapy Pub Date : 2025-02-13 Epub Date: 2024-12-31 DOI:10.1128/aac.01387-24

Kimberly C Claeys, Patricia J Simner, Tsigereda Tekle, Anthony D Harris, Emily Jacobs, Sara E Cosgrove, Pranita D Tamma

{"title":"头孢曲松预测肠杆菌分离株对口服高代头孢菌素的敏感性有多准确？","authors":"Kimberly C Claeys, Patricia J Simner, Tsigereda Tekle, Anthony D Harris, Emily Jacobs, Sara E Cosgrove, Pranita D Tamma","doi":"10.1128/aac.01387-24","DOIUrl":null,"url":null,"abstract":"The reliability of ceftriaxone for inferring susceptibility to higher-generation oral cephalosporins is unknown. Overall, ceftriaxone susceptibility predicted susceptibility to cefuroxime (89%), cefdinir (86%), cefpodoxime (90%), and cefixime (94%) based on disk diffusion results for 409 consecutive Enterobacterales bloodstream isolates from unique patients. Susceptibility percentages to the four oral cephalosporins ranged from 92% to 99% when limited to Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, or Proteus mirabilis isolates susceptible to ceftriaxone.","PeriodicalId":8152,"journal":{"name":"Antimicrobial Agents and Chemotherapy","volume":" ","pages":"e0138724"},"PeriodicalIF":4.1000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823661/pdf/","citationCount":"0","resultStr":"{\"title\":\"How accurate is ceftriaxone at predicting susceptibility of enterobacterales isolates to oral higher-generation cephalosporins?\",\"authors\":\"Kimberly C Claeys, Patricia J Simner, Tsigereda Tekle, Anthony D Harris, Emily Jacobs, Sara E Cosgrove, Pranita D Tamma\",\"doi\":\"10.1128/aac.01387-24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The reliability of ceftriaxone for inferring susceptibility to higher-generation oral cephalosporins is unknown. Overall, ceftriaxone susceptibility predicted susceptibility to cefuroxime (89%), cefdinir (86%), cefpodoxime (90%), and cefixime (94%) based on disk diffusion results for 409 consecutive Enterobacterales bloodstream isolates from unique patients. Susceptibility percentages to the four oral cephalosporins ranged from 92% to 99% when limited to Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, or Proteus mirabilis isolates susceptible to ceftriaxone.\",\"PeriodicalId\":8152,\"journal\":{\"name\":\"Antimicrobial Agents and Chemotherapy\",\"volume\":\" \",\"pages\":\"e0138724\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2025-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823661/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Antimicrobial Agents and Chemotherapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1128/aac.01387-24\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/31 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Antimicrobial Agents and Chemotherapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1128/aac.01387-24","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/31 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

头孢曲松用于推断对更一代口服头孢菌素易感性的可靠性尚不清楚。总体而言，基于从个别患者连续分离的409株肠杆菌血液分离株的盘扩散结果，头孢曲松敏感性预测对头孢呋辛（89%）、头孢地尼（86%）、头孢多肟（90%）和头孢克肟（94%）的敏感性。当只限于对头孢曲松敏感的大肠埃希菌、肺炎克雷伯菌、产氧克雷伯菌或奇异变形杆菌分离株时，对四种口服头孢菌素的敏感性百分比从92%到99%不等。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

How accurate is ceftriaxone at predicting susceptibility of enterobacterales isolates to oral higher-generation cephalosporins?

The reliability of ceftriaxone for inferring susceptibility to higher-generation oral cephalosporins is unknown. Overall, ceftriaxone susceptibility predicted susceptibility to cefuroxime (89%), cefdinir (86%), cefpodoxime (90%), and cefixime (94%) based on disk diffusion results for 409 consecutive Enterobacterales bloodstream isolates from unique patients. Susceptibility percentages to the four oral cephalosporins ranged from 92% to 99% when limited to Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, or Proteus mirabilis isolates susceptible to ceftriaxone.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Antimicrobial Agents and Chemotherapy 医学-微生物学

CiteScore

10.00

自引率

8.20%

发文量

762

审稿时长

3 months

期刊介绍： Antimicrobial Agents and Chemotherapy (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy.