生物系统中单线态氧报告的双标记聚合物胶束

IF 3.2 3区工程技术 Q2 CHEMISTRY, PHYSICAL

Molecular Systems Design & Engineering Pub Date : 2024-11-13 DOI:10.1039/D4ME00105B

Yasuhiro Nakagawa, Hayato Laurence Mizuno, Yuta Ushimaru, Jumpei Norimatsu, Kazunori Igarashi, Keita Masuda, Madoka Takai, Yasutaka Anraku and Horacio Cabral

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引用次数: 0

摘要

可视化生物系统中的单线态氧（1O2）可以极大地提高我们对其生物学作用的理解，并提供新的诊断和治疗方法。然而，氧是不稳定的和高活性的，这使得它在生命系统中的检测成为一个重大挑战。为了解决这个问题，我们开发了双标记的聚合物胶束，旨在追踪o2的位置和水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dual-labelled polymeric micelles for singlet oxygen reporting in biological systems†

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Dual-labelled polymeric micelles for singlet oxygen reporting in biological systems†

Visualizing singlet oxygen (¹O₂) in biological systems could greatly enhance our understanding of its biological roles and offer new diagnostics and therapeutics. However, ¹O₂ is unstable and highly reactive, making its detection in living systems a significant challenge. To address this, we have developed dually-labelled polymeric micelles designed to trace both the location and levels of ¹O₂.

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来源期刊

Molecular Systems Design & Engineering Engineering-Biomedical Engineering

CiteScore

6.40

自引率

2.80%

发文量

144

期刊介绍： Molecular Systems Design & Engineering provides a hub for cutting-edge research into how understanding of molecular properties, behaviour and interactions can be used to design and assemble better materials, systems, and processes to achieve specific functions. These may have applications of technological significance and help address global challenges.