{"title":"探索患者观点：深部脑刺激作为轻度认知障碍新治疗方法的结构化访谈研究。","authors":"Pooja Venkatesh, Bradley Lega, Michael Rubin","doi":"10.1080/21507740.2024.2438033","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Limited treatments for Mild Cognitive Impairment (MCI) highlight the need to explore innovations including Deep Brain Stimulation (DBS), with patient perspectives key to ethical protocol development.</p><p><strong>Methods: </strong>Seven MCI patients and four care partners were interviewed (Feb 2023-Jan 2024) about daily MCI challenges, desired treatment outcomes, and views on DBS. Thematic analysis following COREQ guidelines identified key themes.</p><p><strong>Results: </strong>DBS was a novel concept for all (7/7), and most expressed interest (6/7) despite concerns about invasiveness (6/7) and preference to exhaust medications first (4/7). Care partners (4/4) shared concerns about invasiveness and emphasized proven efficacy. Key deciding factors included the involved procedural risk (6/7), desired significant outcomes (6/7), and prior testing for MCI (7/7). Most participants (6/7) were hesitant to be the first to try DBS, while one was willing.</p><p><strong>Conclusion: </strong>Patient and care partner insights on DBS for MCI are crucial for balancing innovation with ethical, patient-centered research.</p>","PeriodicalId":39022,"journal":{"name":"AJOB Neuroscience","volume":" ","pages":"1-12"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Exploring Patient Perspectives: A Structured Interview Study on Deep Brain Stimulation as a Novel Treatment Approach for Mild Cognitive Impairment.\",\"authors\":\"Pooja Venkatesh, Bradley Lega, Michael Rubin\",\"doi\":\"10.1080/21507740.2024.2438033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Limited treatments for Mild Cognitive Impairment (MCI) highlight the need to explore innovations including Deep Brain Stimulation (DBS), with patient perspectives key to ethical protocol development.</p><p><strong>Methods: </strong>Seven MCI patients and four care partners were interviewed (Feb 2023-Jan 2024) about daily MCI challenges, desired treatment outcomes, and views on DBS. Thematic analysis following COREQ guidelines identified key themes.</p><p><strong>Results: </strong>DBS was a novel concept for all (7/7), and most expressed interest (6/7) despite concerns about invasiveness (6/7) and preference to exhaust medications first (4/7). Care partners (4/4) shared concerns about invasiveness and emphasized proven efficacy. Key deciding factors included the involved procedural risk (6/7), desired significant outcomes (6/7), and prior testing for MCI (7/7). Most participants (6/7) were hesitant to be the first to try DBS, while one was willing.</p><p><strong>Conclusion: </strong>Patient and care partner insights on DBS for MCI are crucial for balancing innovation with ethical, patient-centered research.</p>\",\"PeriodicalId\":39022,\"journal\":{\"name\":\"AJOB Neuroscience\",\"volume\":\" \",\"pages\":\"1-12\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"AJOB Neuroscience\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/21507740.2024.2438033\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Neuroscience\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"AJOB Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/21507740.2024.2438033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Neuroscience","Score":null,"Total":0}
Exploring Patient Perspectives: A Structured Interview Study on Deep Brain Stimulation as a Novel Treatment Approach for Mild Cognitive Impairment.
Introduction: Limited treatments for Mild Cognitive Impairment (MCI) highlight the need to explore innovations including Deep Brain Stimulation (DBS), with patient perspectives key to ethical protocol development.
Methods: Seven MCI patients and four care partners were interviewed (Feb 2023-Jan 2024) about daily MCI challenges, desired treatment outcomes, and views on DBS. Thematic analysis following COREQ guidelines identified key themes.
Results: DBS was a novel concept for all (7/7), and most expressed interest (6/7) despite concerns about invasiveness (6/7) and preference to exhaust medications first (4/7). Care partners (4/4) shared concerns about invasiveness and emphasized proven efficacy. Key deciding factors included the involved procedural risk (6/7), desired significant outcomes (6/7), and prior testing for MCI (7/7). Most participants (6/7) were hesitant to be the first to try DBS, while one was willing.
Conclusion: Patient and care partner insights on DBS for MCI are crucial for balancing innovation with ethical, patient-centered research.
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