2015-2020年大型急诊科住院患者血清乙醇浓度与性别和年龄的关系

IF 2.7 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Aase Bratberg, Ilah Nygaard, Kari Løhne, Ingebjørg Gustavsen, Mimi Stokke Opdal
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引用次数: 0

摘要

我们研究了在一家大型急诊科(ED)入院时检测血清乙醇浓度(SEC)的患者数量,以及SEC与性别和年龄的关系。用酶法对SEC进行分析。我们从实验室信息系统中检索2015-2020年间急诊科患者样本中的SEC。总共有174 378名患者入院,7.3%的患者接受了SEC检测,其中35.3%的患者检测呈阳性。接受检测的患者比例从2015年的4.8%增加到2020年的14.4%。共有416例患者有一个以上的SEC阳性。对于个体数据,我们纳入了每个患者的第一个阳性检测,n = 3607。其中73%是男性,27%是女性。男性和女性的中位数SEC均为1.9 g/L。约4.4%的人SEC≥3.5 g/L。30-59岁患者的中位SEC比12-29岁和≥60岁年龄组高0.2 g/L。总之,接受检测的患者百分比的增加并没有导致乙醇阳性检测的相应增加。男性占多数,男性和女性的中位数SEC相同,在30-59岁年龄组中最高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Serum Ethanol Concentrations in Relation to Sex and Age in Patients Admitted to a Large Emergency Department During 2015–2020

Serum Ethanol Concentrations in Relation to Sex and Age in Patients Admitted to a Large Emergency Department During 2015–2020

We examined the number of patients tested for serum ethanol concentration (SEC) at admission to a large Emergency Department (ED) and the relationship of SEC with sex and age. SEC was analysed by enzymatic method. We retrieved SEC in patient samples from the ED during 2015–2020 from the laboratory information system. Altogether, 174 378 patients were admitted, and 7.3% were tested for SEC. Of these, 35.3% had a positive test. The percentage of patients tested increased from 4.8% in 2015 to 14.4% in 2020. A total of 416 patients had more than one positive SEC. For individual data, we included the first positive test per patient, n = 3607. Of these, 73% were men and 27% were women. The median SEC for both men and women was 1.9 g/L. About 4.4% had a SEC ≥ 3.5 g/L. The median SEC in patients aged 30–59 years was 0.2 g/L higher than the 12–29 and ≥ 60 age groups. In conclusion, the increase in the percentage of patients tested did not lead to a corresponding increase in ethanol-positive tests. There was a large predominance of men, the median SEC was the same for men and women and highest in the 30–59 age group.

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来源期刊
CiteScore
5.60
自引率
6.50%
发文量
126
审稿时长
1 months
期刊介绍: Basic & Clinical Pharmacology and Toxicology is an independent journal, publishing original scientific research in all fields of toxicology, basic and clinical pharmacology. This includes experimental animal pharmacology and toxicology and molecular (-genetic), biochemical and cellular pharmacology and toxicology. It also includes all aspects of clinical pharmacology: pharmacokinetics, pharmacodynamics, therapeutic drug monitoring, drug/drug interactions, pharmacogenetics/-genomics, pharmacoepidemiology, pharmacovigilance, pharmacoeconomics, randomized controlled clinical trials and rational pharmacotherapy. For all compounds used in the studies, the chemical constitution and composition should be known, also for natural compounds.
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