仲硝基烷烃作为α-硝基自由基和一氧化氮源催化烯烃好氧碳氧化反应

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2024-12-25 DOI:10.1021/acs.orglett.4c04483

Hyesoo Park, Soumyadeep Roy Chowdhury, Hun Young Kim, Kyungsoo Oh

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引用次数: 0

摘要

仲硝基烷烃的好氧硝基-亚硝酸盐异构化假定是通过α-硝基烷基自由基的中间体进行的，其中相应的nef型产物、酮和一氧化氮可以作为副产物得到。为了探索仲硝基烷烃催化烯烃好氧碳肟化反应，研究了KSeCN和TBAI相转移催化反应。目前烯烃的好氧碳氧化利用硝基烷烃作为自由基和一氧化氮的来源，在水中没有外部氧化剂和预功能化硝基烷烃。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Catalytic Aerobic Carbooximation of Alkenes Using Secondary Nitroalkanes as Both α-Nitro Alkyl Radical and Nitrogen Monoxide Sources

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Catalytic Aerobic Carbooximation of Alkenes Using Secondary Nitroalkanes as Both α-Nitro Alkyl Radical and Nitrogen Monoxide Sources

Aerobic nitro-nitrite isomerization of secondary nitroalkanes is postulated to proceed via the intermediacy of the α-nitro alkyl radical, where the corresponding Nef-type products, ketones, and nitrogen monoxide can be obtained as byproducts. To explore the catalytic aerobic carbooximation of alkenes using secondary nitroalkanes, phase-transfer catalysis of KSeCN and TBAI has been developed. The current aerobic carbooximation of alkenes utilizes nitroalkanes as both radical and nitrogen monoxide sources in water without external oxidants and prefunctionalized nitroalkanes.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.