meso-5, 15-Bis [3 - (iso-propyl-idenegalacto-pyran-oxy) phen-yl] -10年,20-bis——(4-methyl-phen-yl)卟啉。

IUCrData Pub Date : 2024-10-01 DOI:10.1107/S2414314624010289

Mickey Vinodh , Fatemeh H. Alipour , Talal F. Al-Azemi

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引用次数: 0

摘要

本文报道了糖基化卟啉（P_Gal2）体系C70H70N4O12的晶体结构，其中两个异丙基保护的半乳糖片段连接在取代的四芳基卟啉的中间位上。这种结构揭示了亲本卟啉是平面的，半乳糖部分位于卟啉大环的上下。这种取向可能会阻止卟啉-卟啉h型聚集，潜在地提高其在光动力治疗中作为光敏剂的效率。在该晶体网络中观察到相邻的P_Gal2体系之间显著的非键C-H⋯O和C-H⋯π相互作用。此外，每种卟啉的托基都能与邻近卟啉的离域π-体系发生π-π相互作用。

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meso-5,15-Bis[3-(isopropylidenegalactopyranoxy)phenyl]-10,20-bis(4-methylphenyl)porphyrin

The crystal structure, non-bonding interactions and packing features of a novel galactose conjugated porphyrin are presented and discussed.

The crystal structure of a glycosylated porphyrin (P_Gal2) system, C₇₀H₇₀N₄O₁₂, where two isopropylidene protected galactose moieties are attached to the meso position of a substituted tetraaryl porphyrin is reported. This structure reveals that the parent porphyrin is planar, with the galactose moieties positioned above and below the porphyrin macrocycle. This orientation likely prevents porphyrin–porphyrin H-type aggregation, potentially enhancing its efficiency as a photosensitizer in photodynamic therapy. Notable non-bonding C—H⋯O and C—H⋯π interactions among adjacent P_Gal2 systems are observed in this crystal network. Additionally, the tolyl groups of each porphyrin can engage in π–π interactions with the delocalized π-systems of neighboring porphyrins.

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来源期刊

IUCrData

CiteScore

0.30

自引率

0.00%

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