[1例慢性肾衰竭患者COVID-19后后部可逆性脑病综合征]。

Q4 Medicine
Clinical Neurology Pub Date : 2025-01-29 Epub Date: 2024-12-21 DOI:10.5692/clinicalneurol.cn-002013
Masato Kochi, Yoshiki Yokoyama
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引用次数: 0

摘要

一名61岁的慢性肾衰竭患者发生不明原因的栓塞性中风,接受华法林治疗。五周后,患者感染了冠状病毒病(COVID-19)。新冠肺炎发病后第6天出现高血压(>200‍mmHg)和意识障碍。CT示双侧小脑半球对称低密度区。MRI显示双侧小脑半球和脑桥在t2加权和液体衰减反转恢复图像上出现高强度病变。此外,在表观扩散系数图上,小脑病变表现为高强度区。基于这些发现,诊断为后可逆性脑病综合征(PRES)。患者经降压药治疗后,意识水平逐渐改善。一个月后MRI显示病变消失。如果COVID-19患者的脑部CT显示低密度病变,特别是存在慢性肾衰竭或高血压等PRES危险因素的患者,应考虑PRES。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Posterior reversible encephalopathy syndrome after COVID-19 in a patient with chronic renal failure].

A 61-year-old man with chronic renal failure had an embolic stroke of undetermined source that was treated with warfarin. Five weeks later, the patient contracted coronavirus disease (COVID-19). Six days after the onset of COVID-19, high blood pressure (>200 ‍mmHg) and consciousness disturbance were reported. CT demonstrated symmetrical hypodensity areas in the bilateral cerebellar hemispheres. MRI revealed hyperintensity lesions in the bilateral cerebellar hemispheres and pons on the T2-weighted and fluid-attenuated inversion recovery images. Moreover, cerebellar lesions appeared as hyperintensity areas on apparent diffusion coefficient mapping. Based on these findings, a diagnosis of posterior reversible encephalopathy syndrome (PRES) was made. The patient was treated with antihypertensive drugs, and the consciousness level improved gradually. MRI after one month showed that the lesions had disappeared. PRES should be considered if the brain CT of patients with COVID-19 shows a low-density lesion, especially in patients with risk factors for PRES such as chronic renal failure or hypertension.

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来源期刊
Clinical Neurology
Clinical Neurology Medicine-Neurology (clinical)
CiteScore
0.30
自引率
0.00%
发文量
147
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