基于上转换纳米粒子和氧化石墨烯的复合材料综述：以实体瘤为中心的开发和治疗应用

IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

International Journal of Mechanical and Materials Engineering Pub Date : 2024-12-20 DOI:10.1186/s40712-024-00187-3

Kabirdas B. Ghorpade, Manoj Kumar, Sanjay Tiwari

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A review on composites based on upconversion nanoparticles and graphene oxide: development and theranostic applications centered at solid tumors

Upconversion nanoparticles (UCNPs) have attracted considerable interest for the imaging of solid tumors because of their unique optical features. These applications can be expanded towards anticancer therapeutics by developing UCNP-graphene oxide (GO) composites. This strategy addresses low loading capacity and poor dispersibility of UCNPs in physiological media. These aspects have been covered in this article. We begin by discussing the synthesis methods and challenges associated with UCNPs, along with their surface modification strategies. Next, we describe the approaches of designing UCNP-GO composites and their applications in imaging, biosensing, and different therapeutic platforms.