刺激背根神经节可改善克罗恩病衰弱性腹痛的功能:12个月随访

Ahmed Khawer , Harman Chopra , Tariq AlFarra , Eellan Sivanesan
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引用次数: 0

摘要

背景:克罗恩病(CD)是一种慢性复发缓解型、免疫性、炎症性肠病,可累及胃肠道的任何部位,最常见的是回肠末端。腹痛是乳糜泻的一个突出的衰弱症状,由于持续的肠道炎症,与疾病严重程度和并发症相关。然而,即使疾病缓解,腹痛也会发生。病例介绍:一名女大学生与克罗恩病的历史被转介严重,慢性腹痛,频繁发作和住院治疗。由于她的难治性衰弱性疼痛,DRG刺激开始于右T11和T12。植入后12个月,患者报告疼痛减轻50- 60%,耐受口服饮食,无餐后疼痛,自植入以来没有出现耀斑,整体功能和生活质量得到改善。结论:本报告显示了DRG刺激治疗炎症性肠病(如克罗恩病)难治性慢性腹痛的治疗潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dorsal root ganglion stimulation provides functional improvement from debilitating abdominal pain in Crohn's disease: A 12-month follow-up

Background

Crohn's disease (CD) is a chronic relapsing-remitting, immunological, inflammatory bowel disease involving any part of the gastrointestinal tract, most commonly, the terminal ileum. Abdominal pain is a prominent debilitating symptom of CD due to continuous intestinal inflammation, associated with disease severity and complications. However, abdominal pain has shown to occur even with disease remission.

Case presentation

A female college student with a history of Crohn's Disease was referred for severe, chronic abdominal pain, with frequent flare-ups and hospitalizations. Due to her refractory debilitating pain, DRG stimulation was initiated with leads placed at right T11 and T12. Twelve months post-implantation, the patient reports 50–60 % reduction in pain, tolerance of an oral diet without postprandial pain, no occurrence of flares since implant, and an overall improvement in function and quality of life.

Conclusion

This report showcases the therapeutic potential of DRG stimulation in managing intractable chronic abdominal pain in inflammatory bowel diseases such as Crohn's disease.
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