影响心力衰竭患者药物依从性的因素——一项对心脏保健提供者的调查

IF 6.3 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Ingibjorg Gunnthorsdottir, Anna Birna Almarsdottir, Karl Andersen, Anna I Gunnarsdottir, Erla Svansdottir, Hafsteinn Einarsson, Inga Jona Ingimarsdottir
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引用次数: 0

摘要

坚持用药方案是缓解心衰(HF)症状和减缓疾病进展的关键行为。本研究探讨了心脏保健提供者对HF患者药物依从性(MA)影响因素的看法和经验,研究结果有助于制定HF特异性MA评估量表。采用横截面混合方法设计,我们进行了一项在线调查,其中包括封闭式和开放式问题,分发给在冰岛国立大学医院工作的心脏保健提供者。该调查包括103个问题,分为18个主题。分析包括参与者对封闭式回答的描述性统计和简化评分。自由文本的回答分为专题类别,然后分为次专题。在被邀请的104名医疗保健提供者中,73人(70%)参加了。被确定为支持MA最有利的关键因素包括支持性医患关系(97%)、选择合适的药物配方(96%)、家庭医疗保健支持(95%)和药房多剂量配药(93%)。最年轻和最年长的心衰患者被认为是药物依从性风险最高的,尤其是在男性中。其他估计风险增加的患者包括酒精和/或药物滥用患者(89%),对药物效果了解有限的患者(89%),认为药物无用的患者(88%)和认知障碍患者(86%)。大多数参与者(73%)同意医疗保健提供者应在临床护理中评估和记录MA。这些发现为心脏保健提供者认为影响心衰患者不依从性的因素提供了一个全面的概述,有助于HF特异性MA量表的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Influencing Medication Adherence in Heart Failure Patients-A Survey among Cardiac Healthcare Providers.

Adhering to medication regimens is key behavior to alleviate symptoms and slow disease progression in heart failure (HF). This study explores cardiac healthcare providers' perceptions and experiences of factors influencing medication adherence (MA) in HF patients, with findings contributing to developing a HF-specific MA assessment scale. Using a cross-sectional, mixed methods design, we conducted an online survey with both closed and open-ended questions distributed to cardiac healthcare providers, working at the National University Hospital in Iceland. The survey consisted of 103 questions divided into 18 themes. Analysis included descriptive statistics of the participants' responses to closed responses with simplified scoring. Free-text responses were grouped into thematic categories and then into subthemes. Of 104 healthcare providers invited, 73 (70%) participated. Key factors identified as most beneficial for supporting MA included supportive patient-provider relationships (97%), selecting suitable drug formulation (96%), healthcare support at home (95%), and multi-dose dispensing from pharmacies (93%). The youngest and oldest HF patients were believed to be at the highest risk of medication non-adherence, particularly among males. Other patients estimated at increased risk included those with alcohol and/or substance abuse (89%), those with limited knowledge of medication effects (89%), those perceiving medication as useless (88%), and those with cognitive impairment (86%). Most participants (73%) agreed that healthcare providers should assess and document MA in clinical care. These findings provide a comprehensive overview of factors that cardiac healthcare providers believe influence non-adherence in HF patients, contributing to the development of a HF-specific MA scale.

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来源期刊
CiteScore
12.70
自引率
7.50%
发文量
290
审稿时长
2 months
期刊介绍: Clinical Pharmacology & Therapeutics (CPT) is the authoritative cross-disciplinary journal in experimental and clinical medicine devoted to publishing advances in the nature, action, efficacy, and evaluation of therapeutics. CPT welcomes original Articles in the emerging areas of translational, predictive and personalized medicine; new therapeutic modalities including gene and cell therapies; pharmacogenomics, proteomics and metabolomics; bioinformation and applied systems biology complementing areas of pharmacokinetics and pharmacodynamics, human investigation and clinical trials, pharmacovigilence, pharmacoepidemiology, pharmacometrics, and population pharmacology.
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