误分类治疗倾向得分的非参数估计。

IF 1.8 4区 医学 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Li-Pang Chen
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引用次数: 0

摘要

在因果推理的框架中,平均治疗效果(ATE)是一个关键问题。为了对其进行估计,基于倾向分数的估计方法及其变体被广泛采用。然而,大多数现有的方法都是在假设二元处理是精确测量的情况下发展起来的。此外,倾向分数通常被表述为关于混杂因素的参数模型。然而,在二元处理中存在测量误差以及处理与混杂因素之间存在非线性关系的情况下,如果忽略这些特征,现有方法将不再有效,并且可能产生有偏差的推断结果。在本文中,我们首先分析了ATE估计的影响,并推导了当处理受到测量误差污染时ATE估计量的偏差。在此基础上,我们开发了一种有效的方法来解决二元分类错误。在校正处理条件下,采用随机森林方法估计非线性混杂因素的倾向得分,并推导出ATE的估计量。建立了消差估计量的渐近性质。数值研究还对所提出的估计器的有限样本性能进行了评估,数值结果验证了校正测量误差影响的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nonparametric Estimation for Propensity Scores With Misclassified Treatments.

In the framework of causal inference, average treatment effect (ATE) is one of crucial concerns. To estimate it, the propensity score based estimation method and its variants have been widely adopted. However, most existing methods were developed by assuming that binary treatments are precisely measured. In addition, propensity scores are usually formulated as parametric models with respect to confounders. However, in the presence of measurement error in binary treatments and nonlinear relationship between treatments and confounders, existing methods are no longer valid and may yield biased inference results if these features are ignored. In this paper, we first analytically examine the impact of estimation of ATE and derive biases for the estimator of ATE when treatments are contaminated with measurement error. After that, we develop a valid method to address binary treatments with misclassification. Given the corrected treatments, we adopt the random forest method to estimate the propensity score with nonlinear confounders accommodated and then derive the estimator of ATE. Asymptotic properties of the error-eliminated estimator are established. Numerical studies are also conducted to assess the finite sample performance of the proposed estimator, and numerical results verify the importance of correcting for measurement error effects.

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来源期刊
Statistics in Medicine
Statistics in Medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.40
自引率
10.00%
发文量
334
审稿时长
2-4 weeks
期刊介绍: The journal aims to influence practice in medicine and its associated sciences through the publication of papers on statistical and other quantitative methods. Papers will explain new methods and demonstrate their application, preferably through a substantive, real, motivating example or a comprehensive evaluation based on an illustrative example. Alternatively, papers will report on case-studies where creative use or technical generalizations of established methodology is directed towards a substantive application. Reviews of, and tutorials on, general topics relevant to the application of statistics to medicine will also be published. The main criteria for publication are appropriateness of the statistical methods to a particular medical problem and clarity of exposition. Papers with primarily mathematical content will be excluded. The journal aims to enhance communication between statisticians, clinicians and medical researchers.
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