致编辑的信：肿瘤与免疫相互作用的空间邻近性可预测肝细胞癌患者的预后。

IF 2.8 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Discover. Oncology Pub Date : 2024-12-18 DOI:10.1007/s12672-024-01666-x

Gaoyao Peng, Jiangfa Li, Xinchou Wang

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Letter to the Editor: Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular carcinoma.

We read with interest the study entitled "Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular "in Hepatology (Maestri E, Kedei N, Khatib S, et al. in Hepatology 79(4):768-79, 2024). This study utilized highly multiplexed CODEX imaging to comprehensively analyze the spatial interactions between tumor and immune cells in hepatocellular carcinoma (HCC), yielding several meaningful findings and innovatively proposing the concept of the spatial neighborhood of immune cell infiltration and confirming its association with patient prognosis. After reading the article carefully, we have some suggestions to point out.

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