多巴酚丁胺诱发慢性肾病患者多灶性肌阵挛。

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Manjappa Mahadevappa, Sakeer Hussain, Shasthara Paneyala, U S Dinesh Kumar
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引用次数: 0

摘要

药物不良反应(adr)在临床实践中很常见,特别是在多种合并症和多种用药的患者中。与药物相关的不良反应可能是轻微的或危及生命的。许多现有的不良反应评估量表和药物警戒规划简化了不良反应的早期诊断和管理。多巴酚丁胺是一种常用的肌力药物,用于器质性心脏病、心脏手术、心脏骤停或急性心肌梗死后继发的收缩力下降引起的心血管失代偿。多巴酚丁胺相关的不良反应主要是由于交感神经过度刺激引起胸部不适、心悸、震颤、头痛、呼吸短促、高血压、恶心、呕吐和嗜酸性心肌炎。肌阵挛是一种神经系统副作用,很少由多巴酚丁胺输注引起,特别是在慢性肾脏疾病(CKD)患者中。我们报告一例罕见的多巴酚丁胺诱导的多局灶性肌阵挛患者在失代偿性心力衰竭的管理期间CKD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dobutamine induced multifocal myoclonus in a patient with chronic kidney disease.

Adverse drug reactions (ADRs) are common in clinical practice, especially among patients with multiple comorbidities and polypharmacy. The ADRs associated with medications may be minor or life-threatening. Many available ADR assessment scales and pharmacovigilance programmes have streamlined the early diagnosis and management of ADRs. Dobutamine is a commonly used inotropic agent in patients with cardiovascular decompensation which is caused by depressed contractility secondary to organic heart disease, cardiac surgery, cardiac arrest or acute myocardial infarction. Dobutamine-associated adverse effects are mainly due to sympathetic overstimulation causing chest discomfort, palpitations, tremors, headache, shortness of breath, hypertension, nausea, vomiting and eosinophilic myocarditis. Myoclonus is a neurological side effect that may be rarely caused by dobutamine infusion, especially among patients with chronic kidney disease (CKD). We are reporting a rare case of dobutamine-induced multifocal myoclonus in a patient with CKD during the management of decompensated heart failure.

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来源期刊
BMJ Case Reports
BMJ Case Reports Medicine-Medicine (all)
CiteScore
1.40
自引率
0.00%
发文量
1588
期刊介绍: BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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