鉴定具有组织特异性和疾病因果性的生物标记物的范例。

IF 2.2 3区生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Omics A Journal of Integrative Biology Pub Date : 2025-01-01 Epub Date: 2024-12-16 DOI:10.1089/omi.2024.0194

Biaoyang Lin, Yingying Ma, Hongyun Yang, Xixiong Kang

{"title":"鉴定具有组织特异性和疾病因果性的生物标记物的范例。","authors":"Biaoyang Lin, Yingying Ma, Hongyun Yang, Xixiong Kang","doi":"10.1089/omi.2024.0194","DOIUrl":null,"url":null,"abstract":"The journey of a biomarker from analytical and clinical validation to clinical and public health utility is laden with a host of challenges. This opinion piece and innovation analysis presents an approach to biomarker discovery and development with a focus on tissue specificity and disease causality, using the case of hepatic disease.","PeriodicalId":19530,"journal":{"name":"Omics A Journal of Integrative Biology","volume":" ","pages":"5-7"},"PeriodicalIF":2.2000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Paradigm to Identify Biomarkers with Tissue Specificity and Disease Causality.\",\"authors\":\"Biaoyang Lin, Yingying Ma, Hongyun Yang, Xixiong Kang\",\"doi\":\"10.1089/omi.2024.0194\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The journey of a biomarker from analytical and clinical validation to clinical and public health utility is laden with a host of challenges. This opinion piece and innovation analysis presents an approach to biomarker discovery and development with a focus on tissue specificity and disease causality, using the case of hepatic disease.\",\"PeriodicalId\":19530,\"journal\":{\"name\":\"Omics A Journal of Integrative Biology\",\"volume\":\" \",\"pages\":\"5-7\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Omics A Journal of Integrative Biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1089/omi.2024.0194\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/16 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Omics A Journal of Integrative Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1089/omi.2024.0194","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/16 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

生物标志物从分析和临床验证到临床和公共卫生用途的旅程充满了许多挑战。这篇观点文章和创新分析提出了一种生物标志物发现和开发的方法，重点关注组织特异性和疾病因果关系，以肝病为例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A Paradigm to Identify Biomarkers with Tissue Specificity and Disease Causality.

The journey of a biomarker from analytical and clinical validation to clinical and public health utility is laden with a host of challenges. This opinion piece and innovation analysis presents an approach to biomarker discovery and development with a focus on tissue specificity and disease causality, using the case of hepatic disease.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Omics A Journal of Integrative Biology 生物-生物工程与应用微生物

CiteScore

6.00

自引率

12.10%

发文量

审稿时长

3 months

期刊介绍： OMICS: A Journal of Integrative Biology is the only peer-reviewed journal covering all trans-disciplinary OMICs-related areas, including data standards and sharing; applications for personalized medicine and public health practice; and social, legal, and ethics analysis. The Journal integrates global high-throughput and systems approaches to 21st century science from “cell to society” – seen from a post-genomics perspective.