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IF 2.1 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES

Journal of evaluation in clinical practice Pub Date : 2024-12-16 DOI:10.1111/jep.14260

Yanmo Yang, Qinxuan Li, Mi Zhou

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引用次数: 0

摘要

研究目的本研究旨在探讨临床药师在多学科团队中指导卵巢癌（OC）患者营养治疗的作用，以及药物营养干预在整体管理和用药方面的意义：我们对妇科肿瘤病房的 59 名卵巢癌患者进行了回顾性调查。根据患者接受的不同营养疗法，将其分为常规治疗（CT）组（30 人）和药物治疗（PM）组（29 人）。营养监测指标和临床反应指标用于评估干预效果。对入院和出院时的血清白蛋白（ALB）、血红蛋白（HGB）和前白蛋白（PAB）水平、排气时间、恢复正常饮食时间、首次术后化疗时间和住院时间进行了测量：结果：PM 组的 PAB 和 ALB 指标恢复到入院时的水平；两组之间的差异有统计学意义（P 0.05）。PM组的排气时间、恢复正常饮食时间和术后首次化疗时间明显短于CT组，差异有统计学意义（P 结论：PM组的营养治疗管理与CT组相比具有明显优势：临床药师的营养治疗管理在 OC 患者的抗肿瘤治疗中发挥着关键作用，可有效改善患者的营养状况，从而促进术后快速康复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Practical Study on the Participation of Clinical Pharmacists in Multi-Disciplinary Teams Dealing With Nutrition Intervention Management in Ovarian Cancer

Objective

This study aimed to explore the role of clinical pharmacists in guiding nutritional treatment in a multi-disciplinary team for patients with ovarian cancer (OC) and the significance of pharmaceutical nutritional intervention in overall management and drug administration.

Methods

Fifty-nine patients with OC in our gynaecological oncology ward were retrospectively investigated. The patients were divided into a conventional therapy (CT) group (n = 30) and a pharmaceutical management (PM) group (n = 29) according to different nutritional therapies received. Nutritional monitoring indicators and clinical response indicators were used to evaluate the intervention effect. Serum albumin (ALB), haemoglobin (HGB) and prealbumin (PAB) levels at admission and discharge, exhaust time, time to return to a normal diet, time to first postoperative chemotherapy and length of hospital stay were measured.

Results

The PAB and ALB indicators in the PM group returned to the admission levels; the difference between the two groups was statistically significant (p < 0.05). There was no significant difference in HGB levels between the two groups (p > 0.05). The time to flatus, time to return to normal diet and time to first postoperative chemotherapy in the PM group were significantly shorter than those in the CT group, and the differences had statistical significance (p < 0.05). Patients in the PM group had a significantly shorter hospital stay than those in the CT group (12.5 ± 3.2 days vs 16.8 ± 4.1 days; p = 0.022).

Conclusion

Nutritional treatment management by clinical pharmacists plays a key role in the antitumour treatment of patients with OC, effectively improving their nutritional status and thus promoting rapid postoperative recovery.

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来源期刊

Journal of evaluation in clinical practice 医学-卫生保健

CiteScore

4.80

自引率

4.20%

发文量

143

审稿时长

3-8 weeks

期刊介绍： The Journal of Evaluation in Clinical Practice aims to promote the evaluation and development of clinical practice across medicine, nursing and the allied health professions. All aspects of health services research and public health policy analysis and debate are of interest to the Journal whether studied from a population-based or individual patient-centred perspective. Of particular interest to the Journal are submissions on all aspects of clinical effectiveness and efficiency including evidence-based medicine, clinical practice guidelines, clinical decision making, clinical services organisation, implementation and delivery, health economic evaluation, health process and outcome measurement and new or improved methods (conceptual and statistical) for systematic inquiry into clinical practice. Papers may take a classical quantitative or qualitative approach to investigation (or may utilise both techniques) or may take the form of learned essays, structured/systematic reviews and critiques.