肥胖对腰椎手术术后和围手术期结果的影响,系统回顾与元分析》(The Impact of Obesity on Postoperative and Perioperative Outcomes in Lumbar Spine Surgery, a Systematic Review and Meta Analysis)。

IF 4.9 1区 医学 Q1 CLINICAL NEUROLOGY
Ebubechi Adindu, Devender Singh, Matthew Geck, John Stokes, Eeric Truumees
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引用次数: 0

摘要

背景背景:肥胖在全球范围内越来越普遍,并与各种健康问题有关,包括脊柱相关疾病。先前的研究显示肥胖对脊柱手术结果的影响好坏参半。目的:本荟萃分析旨在评估肥胖对脊柱手术患者围手术期和术后预后的影响。研究设计/背景:我们对前瞻性和回顾性研究进行了系统回顾和荟萃分析,比较了肥胖和非肥胖脊柱手术患者的结果。患者样本:荟萃分析纳入35,639例患者,其中肥胖(BMI≥30 kg/m²)9,369例,非肥胖(BMI < 30 kg/m²)26,270例。结果测量:主要结果包括患者报告的结果测量(PROMs),如Oswestry残疾指数(ODI)和腿部和背部疼痛的视觉模拟量表(VAS)。次要结果包括围手术期测量,如估计失血量(EBL)、手术时间、住院时间(LOS)以及并发症和再手术率。方法:按照PRISMA指南,检索4个数据库进行相关研究。采用Cochrane偏倚风险工具评估纳入研究的质量。使用平均差异来量化PROMs和围手术期结果的差异。比值比用于分析并发症发生率的差异。结果:肥胖患者与非肥胖患者的PROMs相似,差异不超过最小临床重要差异(MCID)。然而,肥胖患者手术时间更长,EBL更大,住院时间更长。他们也有较高的术后并发症,如硬脑膜撕裂、感染和再手术。结论:虽然肥胖与围手术期的某些挑战有关,但肥胖和非肥胖患者在疼痛和残疾方面的术后恢复似乎是相似的。脊柱外科医生应该意识到围手术期风险的增加,但可以向肥胖患者保证术后类似的长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of obesity on postoperative and perioperative outcomes in lumbar spine surgery: a systematic review and meta-analysis.

Background context: Obesity is increasingly prevalent globally and is associated with various health issues, including spine-related disorders. Previous studies have shown mixed results regarding the impact of obesity on spine surgery outcomes.

Purpose: This meta-analysis aims to evaluate the effects of obesity on perioperative and postoperative outcomes in spine surgery patients.

Study design/setting: We performed a systematic review and meta-analysis of prospective and retrospective studies comparing outcomes between obese and nonobese spine surgery patients.

Patient sample: The meta-analysis included 35,639 patients, of which 9,369 were obese (BMI≥30 kg/m²) and 26,270 were nonobese (BMI<30 kg/m²).

Outcome measures: Primary outcomes included patient-reported outcome measures (PROMs) such as the Oswestry Disability Index (ODI) and the Visual Analog Scale (VAS) for leg and back pain. Secondary outcomes involved perioperative measures like estimated blood loss (EBL), operative time, and length of stay (LOS), as well as complication and reoperation rates.

Methods: Following PRISMA guidelines, four databases were searched for relevant studies. The quality of included studies was assessed using the Cochrane Risk of Bias tool. Mean differences were used to quantify the differences in PROMs and perioperative outcomes. Odds ratios were used to analyze differences in complication rates.

Results: Obese patients had similar PROMs compared to nonobese patients, with differences not exceeding the minimal clinically important difference (MCID). However, obese patients experienced longer operative times, greater EBL, and extended hospital stays. They also had higher rates of postoperative complications such as Dural tears, infections, and reoperations.

Conclusions: While obesity is associated with certain perioperative challenges, the postoperative recovery in terms of pain and disability appears comparable between obese and nonobese patients. Spine surgeons should be aware of the increased perioperative risks but can reassure obese patients of similar long-term outcomes postsurgery.

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来源期刊
Spine Journal
Spine Journal 医学-临床神经学
CiteScore
8.20
自引率
6.70%
发文量
680
审稿时长
13.1 weeks
期刊介绍: The Spine Journal, the official journal of the North American Spine Society, is an international and multidisciplinary journal that publishes original, peer-reviewed articles on research and treatment related to the spine and spine care, including basic science and clinical investigations. It is a condition of publication that manuscripts submitted to The Spine Journal have not been published, and will not be simultaneously submitted or published elsewhere. The Spine Journal also publishes major reviews of specific topics by acknowledged authorities, technical notes, teaching editorials, and other special features, Letters to the Editor-in-Chief are encouraged.
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