有效剂量在当前和未来医学中的作用。

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Colin John Martin, Abdullah Abuhaimed
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引用次数: 0

摘要

本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of effective dose in medicine now and into the future.

Effective dose was created as a radiological protection dose quantity linked to risk to enable planning of radiological protection for the control of exposure. Its application and use has evolved from occupational and public exposure during work with radiation sources to medicine and applications in patient dosimetry. Effective dose is the sum of doses to organs and tissues within the body weighted according to their sensitivity to radiation for induction of stochastic effects determined from epidemiological studies of exposed populations. It is based on radiation risks averaged over the population and formulated using reference phantoms. Effective dose has been adopted by the medical community for application to patients and has been instrumental in raisingawareness of doses from medical imaging. However, although effective dose can beused for comparison of doses from different medical procedures, it is not designed forapplication to individual patients. The reasons being that organ doses vary with the stature of the patient and the radiation risks depend on the age and sex of the patient. Moves to more personalised medicine have created a desire for a more individualised approach to patient dosimetry, although support for this progression is not universal. This paper traces the evolution of effective dose and its applications. It reflects on how well effective dose provides a measure of risk for individual patients and examines ways in which a more personalised approach might be developed with reference to computed tomography (CT). It considers differences in dose relating to the sizes of patients and looks at variations in risks of cancer incidence within a population with an age distribution typical of patients and examines how this relates to the risk profile. Possible options for improving the individualisation of dosimetry are discussed. .

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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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