基于张量的图卷积网络用于多模态脑网络分析。

IF 4 3区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Zhaoming Kong, Rong Zhou, Xinwei Luo, Songlin Zhao, Ann B Ragin, Alex D Leow, Lifang He
{"title":"基于张量的图卷积网络用于多模态脑网络分析。","authors":"Zhaoming Kong, Rong Zhou, Xinwei Luo, Songlin Zhao, Ann B Ragin, Alex D Leow, Lifang He","doi":"10.1186/s13040-024-00409-6","DOIUrl":null,"url":null,"abstract":"<p><p>Multimodal brain network analysis enables a comprehensive understanding of neurological disorders by integrating information from multiple neuroimaging modalities. However, existing methods often struggle to effectively model the complex structures of multimodal brain networks. In this paper, we propose a novel tensor-based graph convolutional network (TGNet) framework that combines tensor decomposition with multi-layer GCNs to capture both the homogeneity and intricate graph structures of multimodal brain networks. We evaluate TGNet on four datasets-HIV, Bipolar Disorder (BP), and Parkinson's Disease (PPMI), Alzheimer's Disease (ADNI)-demonstrating that it significantly outperforms existing methods for disease classification tasks, particularly in scenarios with limited sample sizes. The robustness and effectiveness of TGNet highlight its potential for advancing multimodal brain network analysis. The code is available at  https://github.com/rongzhou7/TGNet .</p>","PeriodicalId":48947,"journal":{"name":"Biodata Mining","volume":"17 1","pages":"55"},"PeriodicalIF":4.0000,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622555/pdf/","citationCount":"0","resultStr":"{\"title\":\"TGNet: tensor-based graph convolutional networks for multimodal brain network analysis.\",\"authors\":\"Zhaoming Kong, Rong Zhou, Xinwei Luo, Songlin Zhao, Ann B Ragin, Alex D Leow, Lifang He\",\"doi\":\"10.1186/s13040-024-00409-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Multimodal brain network analysis enables a comprehensive understanding of neurological disorders by integrating information from multiple neuroimaging modalities. However, existing methods often struggle to effectively model the complex structures of multimodal brain networks. In this paper, we propose a novel tensor-based graph convolutional network (TGNet) framework that combines tensor decomposition with multi-layer GCNs to capture both the homogeneity and intricate graph structures of multimodal brain networks. We evaluate TGNet on four datasets-HIV, Bipolar Disorder (BP), and Parkinson's Disease (PPMI), Alzheimer's Disease (ADNI)-demonstrating that it significantly outperforms existing methods for disease classification tasks, particularly in scenarios with limited sample sizes. The robustness and effectiveness of TGNet highlight its potential for advancing multimodal brain network analysis. The code is available at  https://github.com/rongzhou7/TGNet .</p>\",\"PeriodicalId\":48947,\"journal\":{\"name\":\"Biodata Mining\",\"volume\":\"17 1\",\"pages\":\"55\"},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2024-12-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622555/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biodata Mining\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1186/s13040-024-00409-6\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATHEMATICAL & COMPUTATIONAL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biodata Mining","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1186/s13040-024-00409-6","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICAL & COMPUTATIONAL BIOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

多模态脑网络分析通过整合来自多种神经成像模式的信息,可以全面了解神经系统疾病。然而,现有的方法往往难以有效地模拟多模态大脑网络的复杂结构。在本文中,我们提出了一种新的基于张量的图卷积网络(TGNet)框架,该框架将张量分解与多层GCNs相结合,以捕获多模态大脑网络的同质性和复杂的图结构。我们在hiv、双相情感障碍(BP)、帕金森病(PPMI)、阿尔茨海默病(ADNI)四个数据集上对TGNet进行了评估,结果表明,TGNet在疾病分类任务上显著优于现有方法,特别是在样本量有限的情况下。TGNet的鲁棒性和有效性突出了它在推进多模态脑网络分析方面的潜力。代码可在https://github.com/rongzhou7/TGNet上获得。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TGNet: tensor-based graph convolutional networks for multimodal brain network analysis.

Multimodal brain network analysis enables a comprehensive understanding of neurological disorders by integrating information from multiple neuroimaging modalities. However, existing methods often struggle to effectively model the complex structures of multimodal brain networks. In this paper, we propose a novel tensor-based graph convolutional network (TGNet) framework that combines tensor decomposition with multi-layer GCNs to capture both the homogeneity and intricate graph structures of multimodal brain networks. We evaluate TGNet on four datasets-HIV, Bipolar Disorder (BP), and Parkinson's Disease (PPMI), Alzheimer's Disease (ADNI)-demonstrating that it significantly outperforms existing methods for disease classification tasks, particularly in scenarios with limited sample sizes. The robustness and effectiveness of TGNet highlight its potential for advancing multimodal brain network analysis. The code is available at  https://github.com/rongzhou7/TGNet .

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Biodata Mining
Biodata Mining MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
7.90
自引率
0.00%
发文量
28
审稿时长
23 weeks
期刊介绍: BioData Mining is an open access, open peer-reviewed journal encompassing research on all aspects of data mining applied to high-dimensional biological and biomedical data, focusing on computational aspects of knowledge discovery from large-scale genetic, transcriptomic, genomic, proteomic, and metabolomic data. Topical areas include, but are not limited to: -Development, evaluation, and application of novel data mining and machine learning algorithms. -Adaptation, evaluation, and application of traditional data mining and machine learning algorithms. -Open-source software for the application of data mining and machine learning algorithms. -Design, development and integration of databases, software and web services for the storage, management, retrieval, and analysis of data from large scale studies. -Pre-processing, post-processing, modeling, and interpretation of data mining and machine learning results for biological interpretation and knowledge discovery.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信