<26孕周出生婴儿36周矫正龄前体重缓慢和快速增加与6年发育商的关系

IF 1.5 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
American journal of perinatology Pub Date : 2025-06-01 Epub Date: 2024-12-04 DOI:10.1055/a-2462-5220
Masashi Hotta, Katsuya Hirata, Shinya Hirano, Kazuko Wada
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引用次数: 0

摘要

目的:早产儿出生后生长发育受多种因素的影响;然而,极度早产儿的生长与长期预后之间的关系尚不清楚。因此,我们旨在确定极早产儿6岁发育与36周矫正年龄(CA)体重(BW)之间的关系。研究设计:我们进行了一项回顾性观察性研究,研究对象包括在以下地点出生的极早产儿:结果:该研究包括90名婴儿。在DQ≥85的婴儿中,出生后体重SDS变化与中位变化的绝对差异在DQ p = 0.001的婴儿中更为显著。对DQ p进行logistic回归分析后得出结论:对于关键点出生的婴儿:·体重SDS的中位数变化是DQ的关键因素。·体重增长缓慢/快速与6年DQ较低有关。·在新生儿重症监护病房护理中,个人背景可能很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between Slow and Rapid Weight Gain before 36 Weeks of Corrected Age and 6-Year-Developmental Quotient in Infants Born at <26 Weeks of Gestation.

The postnatal growth of preterm infants is influenced by various factors; however, the association between growth and long-term outcomes in extremely preterm infants remains unclear. Therefore, we aimed to determine the association between 6-year development and body weight (BW) at 36 weeks of corrected age (CA) in extremely preterm infants.We conducted a retrospective observational study including extremely preterm infants born at < 26 weeks of gestation. We defined the key standard deviation score (SDS) using BW at birth and evaluated the association between BW-related values at 36 weeks of CA and the 6-year developmental quotient (DQ).This study included 90 infants. The absolute difference between changes in the BW SDS from birth and the median changes in DQ ≥ 85 infants was significantly greater in infants with a DQ < 85 than ≥85 (median [interquartile range]: 0.80 [0.29, 1.31] vs. 0.34 [0.13, 0.55]; p = 0.001). After adjustment by the logistic regression analysis for DQ < 85, the absolute difference was statistically significant (odds ratio: 4.99, 95% confidence interval: 1.71-14.5). The correlation coefficient between the absolute difference and DQ was -0.35 (p < 0.001). There were no significant associations between a DQ < 85 and SDS or changes in SDS from birth.For infants born at <26 weeks of gestation, slow and rapid weight gain were associated with a low 6-year DQ when using values representing individual body sizes at birth. Individual backgrounds should be considered to avoid both slow and rapid weight gain for the growth management of these infants for at least up to 36 weeks of CA. Further research is needed to determine which body size has a positive impact on the long-term outcomes of infants. · The median change in BW SDS was a key factor for DQ.. · Slow/rapid weight gain were related to a low 6-year DQ.. · Individual backgrounds may be important in neonatal intensive care unit care..

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来源期刊
American journal of perinatology
American journal of perinatology 医学-妇产科学
CiteScore
5.90
自引率
0.00%
发文量
302
审稿时长
4-8 weeks
期刊介绍: The American Journal of Perinatology is an international, peer-reviewed, and indexed journal publishing 14 issues a year dealing with original research and topical reviews. It is the definitive forum for specialists in obstetrics, neonatology, perinatology, and maternal/fetal medicine, with emphasis on bridging the different fields. The focus is primarily on clinical and translational research, clinical and technical advances in diagnosis, monitoring, and treatment as well as evidence-based reviews. Topics of interest include epidemiology, diagnosis, prevention, and management of maternal, fetal, and neonatal diseases. Manuscripts on new technology, NICU set-ups, and nursing topics are published to provide a broad survey of important issues in this field. All articles undergo rigorous peer review, with web-based submission, expedited turn-around, and availability of electronic publication. The American Journal of Perinatology is accompanied by AJP Reports - an Open Access journal for case reports in neonatology and maternal/fetal medicine.
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