{"title":"三维技术在浅表近距离治疗中的应用：蕈样真菌病旧领域的新姿态。","authors":"Helena Kamieniecka, Jacek Rutkowski","doi":"10.5114/jcb.2024.143212","DOIUrl":null,"url":null,"abstract":"<p><p>A case report of non-classical treatment choice for mycosis fungoides (MF) presented on the left upper eyelid and forehead. Superficial brachytherapy using 3D technique was prescribed to preserve the lens's functionality, and successfully eliminate malignant lesion. Treatment was conducted with high-dose-rate (HDR) brachytherapy using iridium-192 (<sup>192</sup>Ir) source as a base and Flexitron device as an afterloader. Applicators were immobilized and located near the lesion by manually shaped molds. Doses were calculated using Oncentra treatment planning system (ELEKTA<sup>®</sup>) with 3D models based on CT scans. A 12-month follow-up showed sustained remission without any late toxicity or recurrence of MF skin lesions on the face. The proposed approach utilizing superficial, mold-based HDR brachytherapy to navigate anatomical challenges is demonstrated to be a clinically effective treatment option for MF of the lower eyelid or other dose-limiting locations.</p>","PeriodicalId":51305,"journal":{"name":"Journal of Contemporary Brachytherapy","volume":"16 4","pages":"310-313"},"PeriodicalIF":1.1000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609854/pdf/","citationCount":"0","resultStr":"{\"title\":\"3D technique in superficial brachytherapy: New attitude in old field of mycosis fungoides.\",\"authors\":\"Helena Kamieniecka, Jacek Rutkowski\",\"doi\":\"10.5114/jcb.2024.143212\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A case report of non-classical treatment choice for mycosis fungoides (MF) presented on the left upper eyelid and forehead. Superficial brachytherapy using 3D technique was prescribed to preserve the lens's functionality, and successfully eliminate malignant lesion. Treatment was conducted with high-dose-rate (HDR) brachytherapy using iridium-192 (<sup>192</sup>Ir) source as a base and Flexitron device as an afterloader. Applicators were immobilized and located near the lesion by manually shaped molds. Doses were calculated using Oncentra treatment planning system (ELEKTA<sup>®</sup>) with 3D models based on CT scans. A 12-month follow-up showed sustained remission without any late toxicity or recurrence of MF skin lesions on the face. The proposed approach utilizing superficial, mold-based HDR brachytherapy to navigate anatomical challenges is demonstrated to be a clinically effective treatment option for MF of the lower eyelid or other dose-limiting locations.</p>\",\"PeriodicalId\":51305,\"journal\":{\"name\":\"Journal of Contemporary Brachytherapy\",\"volume\":\"16 4\",\"pages\":\"310-313\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609854/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Contemporary Brachytherapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5114/jcb.2024.143212\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Contemporary Brachytherapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5114/jcb.2024.143212","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/20 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
3D technique in superficial brachytherapy: New attitude in old field of mycosis fungoides.
A case report of non-classical treatment choice for mycosis fungoides (MF) presented on the left upper eyelid and forehead. Superficial brachytherapy using 3D technique was prescribed to preserve the lens's functionality, and successfully eliminate malignant lesion. Treatment was conducted with high-dose-rate (HDR) brachytherapy using iridium-192 (192Ir) source as a base and Flexitron device as an afterloader. Applicators were immobilized and located near the lesion by manually shaped molds. Doses were calculated using Oncentra treatment planning system (ELEKTA®) with 3D models based on CT scans. A 12-month follow-up showed sustained remission without any late toxicity or recurrence of MF skin lesions on the face. The proposed approach utilizing superficial, mold-based HDR brachytherapy to navigate anatomical challenges is demonstrated to be a clinically effective treatment option for MF of the lower eyelid or other dose-limiting locations.
期刊介绍：
The “Journal of Contemporary Brachytherapy” is an international and multidisciplinary journal that will publish papers of original research as well as reviews of articles. Main subjects of the journal include: clinical brachytherapy, combined modality treatment, advances in radiobiology, hyperthermia and tumour biology, as well as physical aspects relevant to brachytherapy, particularly in the field of imaging, dosimetry and radiation therapy planning. Original contributions will include experimental studies of combined modality treatment, tumor sensitization and normal tissue protection, molecular radiation biology, and clinical investigations of cancer treatment in brachytherapy. Another field of interest will be the educational part of the journal.
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