瑜伽对平衡、跌倒和骨代谢的影响:针对健康人的随机对照试验的系统回顾。

IF 4.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Paras Bajaj, Lakshmi Nagendra, Abha Bajaj, Miny Samuel, Manju Chandran
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引用次数: 0

摘要

这项对 18 项研究性实验进行的系统回顾评估了瑜伽对健康人的平衡能力、跌倒风险、跌倒恐惧、骨质密度 (BMD) 和骨转换标志物的影响。瑜伽能明显改善平衡能力,但对骨密度的影响尚无定论。需要进行标准化方案和长期研究:背景:瑜伽对健康人的平衡、跌倒、跌倒恐惧(FOF)、骨矿物质密度(BMD)和骨转换标志物(BTMs)等相互关联的骨骼健康参数的影响尚不明确。我们对随机对照试验(RCT)进行了严格评估,这些试验比较了瑜伽与无干预对照(NIC)或太极拳等参照物对健康人这些参数的影响:方法:我们采用预定方案系统地搜索了多个科学数据库。当报告中存在异质性时,我们对数据进行了定性总结。我们对瑜伽和神经阻滞疗法的比较研究进行了荟萃分析。由于纳入的研究对相同的结果使用了不同的量表,因此我们使用了标准化平均差(SMDs)来进行汇总。我们使用 Cochrane RoB2 随机试验工具评估了偏倚风险,并使用 GRADE 方法对证据的确定性进行了分级:我们评估了 18 项随机试验,共有 1408 名参与者。其中 15 项研究探讨了瑜伽对平衡和/或跌倒或 FOF 的影响,3 项研究探讨了瑜伽对 BMD 和 BTM 的影响。瑜伽类型包括哈达瑜伽、流瑜伽、阿斯汤加瑜伽、艾扬格瑜伽、比克拉姆瑜伽和特别设计的瑜伽方案。研究中使用了 24 种平衡评估工具。研究持续时间从 6 周到 14 个月不等。几乎所有的研究都报告说,与 NIC 相比,瑜伽对平衡有积极的影响;与太极等积极干预相比,瑜伽的效果不劣于 NIC。对四项比较瑜伽和非运动疗法的研究进行的 Meta 分析表明,瑜伽能显著改善静态平衡(SMD = 2.36;95% CI 1.13-3.58;P = 0.0002,I2 = 93% ⊕ ⊕ ⊝)。瑜伽对跌倒和 FOF 的影响好坏参半。两项研究显示瑜伽对骨骼形成有积极影响。只有一项研究发现瑜伽对 BMD 有积极影响。对两项 RCT 进行的 Meta 分析表明,与 NIC 相比,瑜伽对 BMD 没有显著影响。这些研究在瑜伽风格、干预持续时间和评估方法方面表现出很大的异质性:结论:在健康成年人中,低确定性证据显示瑜伽对平衡有益。结论:在健康成年人中,低确定性证据显示瑜伽对平衡有益处,但对 BMD 的影响仍不明确。要想就瑜伽在增强骨骼健康和预防跌倒方面的作用得出更明确的结论,有必要开展标准化方案和更长期的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of yoga on balance, falls, and bone metabolism: a systematic review of randomized controlled trials in healthy individuals.

This systematic review of 18 RCTs assessed the impact of yoga on balance, fall risk, fear of falling, bone mineral density (BMD), and bone turnover markers in healthy individuals. Yoga significantly improved balance but its effects on BMD were inconclusive. Standardised protocols and longer-term studies are needed.

Background: Yoga's effects on interconnected bone health parameters viz balance, falls, fear of falling (FOF), bone mineral density (BMD), and bone turnover markers (BTMs) in healthy individuals are unclear. We critically evaluated randomized controlled trials (RCTs) that compared yoga to no intervention control (NIC) or comparators such as Tai Chi, on these parameters in healthy individuals.

Methods: We systematically searched multiple scientific data bases using a predefined protocol. We summarized data qualitatively when there was heterogeneity in reporting. A meta-analysis of those studies comparing yoga to NIC was done. Since the included studies used different scales for the same outcomes, we used standardised mean differences (SMDs) to allow pooling. We assessed the risk of bias with the Cochrane RoB2 tool for randomized trials and graded certainty of evidence using the GRADE approach.

Results: Eighteen RCTs with 1408 participants were evaluated. Fifteen explored yoga's effects on balance and/or falls or FOF, and three RCTs, its effect on BMD and BTMs. Yoga types included Hatha, Vinyasa, Ashtanga, Iyengar, Bikram, and specially designed yoga protocols. Twenty-four kinds of balance assessment tools were used in the studies. Study durations varied from 6 weeks to 14 months. Almost all the studies reported positive effects of yoga on balance compared to NIC, and non-inferiority when compared to active interventions such as Tai Chi. Meta-analysis of four RCTs comparing yoga to NIC demonstrated significant improvements in static balance with yoga (SMD = 2.36; 95% CI 1.13-3.58; P = 0.0002, I2 = 93% ⊕ ⊕ ⊝ ⊝). Yoga's effects on falls and FOF were mixed. Two studies showed a positive effect of yoga on bone formation. Yoga was found to have a positive effect on BMD in only one study. Meta-analysis of two RCTs showed no significant effect on BMD for yoga compared to NIC. The studies exhibited substantial heterogeneity in terms of yoga styles, intervention durations, and assessment methods.

Conclusion: In healthy adults, low certainty evidence shows that yoga has a beneficial effect on balance. Its effect on BMD remains unclear. Standardised protocols and longer-term research are necessary to facilitate more definitive conclusions on yoga's role in enhancing skeletal health and preventing falls.

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来源期刊
Osteoporosis International
Osteoporosis International 医学-内分泌学与代谢
CiteScore
8.10
自引率
10.00%
发文量
224
审稿时长
3 months
期刊介绍: An international multi-disciplinary journal which is a joint initiative between the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA, Osteoporosis International provides a forum for the communication and exchange of current ideas concerning the diagnosis, prevention, treatment and management of osteoporosis and other metabolic bone diseases. It publishes: original papers - reporting progress and results in all areas of osteoporosis and its related fields; review articles - reflecting the present state of knowledge in special areas of summarizing limited themes in which discussion has led to clearly defined conclusions; educational articles - giving information on the progress of a topic of particular interest; case reports - of uncommon or interesting presentations of the condition. While focusing on clinical research, the Journal will also accept submissions on more basic aspects of research, where they are considered by the editors to be relevant to the human disease spectrum.
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