{"title":"内脏脂肪组织对胃癌术前 CT 肿瘤 T 分期准确性的影响","authors":"Danping Wu, Linjie Bian, Zhongjuan Wang, Jianming Ni, Yigang Chen, Lei Zhang, Xulei Chen","doi":"10.1007/s11604-024-01711-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the impact of the visceral adipose tissue (VAT) area and density on the accuracy of tumor T-staging of gastric cancer in preoperative computed tomography (CT).</p><p><strong>Methods: </strong>This study included 136 patients with gastric cancer in our research center from January 2021 to June 2022. The patients were divided into two groups based on their postoperative pathological results: accurate-staging (matched T-staging evaluated by preoperative CT and postoperative pathology) and inaccurate-staging (unmatched T-staging evaluated by preoperative CT and postoperative pathology) groups. Preoperative CT was performed to assess the VAT area and density, and logistic regression was employed to evaluate the effect of VAT on the accuracy of preoperative-CT-evaluated T-staging of patients with gastric cancer.</p><p><strong>Results: </strong>The accurate-staging group had a significantly higher VAT area (134.64 ± 70.55 cm<sup>2</sup> vs 95.44 ± 66.18 cm<sup>2</sup>, P = 0.003) and significantly lower VAT density (-95.05 ± 12.28 Hounsfield Units [HU] vs - 89.68 ± 13.26 HU, P = 0.027) than the inaccurate-staging group. A low VAT area (P = 0.002) and tumor located in the upper stomach (P = 0.019) were significantly associated with and were independent risk factors for the error of CT-evaluated T-staging. Compared to a VAT area ≥ 81.04 cm<sup>2</sup>, which was used as a reference, the odds ratio (OR) of a VAT area < 81.04 cm<sup>2</sup> for the probability of T-staging mis-assessment was 4.455 (95% confidence interval [CI]: 1.728-11.485).</p><p><strong>Conclusions: </strong>A low VAT area in patients with gastric cancer had adverse effects on preoperative CT-evaluated T-staging.</p>","PeriodicalId":14691,"journal":{"name":"Japanese Journal of Radiology","volume":" ","pages":"656-665"},"PeriodicalIF":2.1000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of visceral adipose tissue on the accuracy of tumor T-staging of gastric cancer in preoperative CT.\",\"authors\":\"Danping Wu, Linjie Bian, Zhongjuan Wang, Jianming Ni, Yigang Chen, Lei Zhang, Xulei Chen\",\"doi\":\"10.1007/s11604-024-01711-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To evaluate the impact of the visceral adipose tissue (VAT) area and density on the accuracy of tumor T-staging of gastric cancer in preoperative computed tomography (CT).</p><p><strong>Methods: </strong>This study included 136 patients with gastric cancer in our research center from January 2021 to June 2022. The patients were divided into two groups based on their postoperative pathological results: accurate-staging (matched T-staging evaluated by preoperative CT and postoperative pathology) and inaccurate-staging (unmatched T-staging evaluated by preoperative CT and postoperative pathology) groups. Preoperative CT was performed to assess the VAT area and density, and logistic regression was employed to evaluate the effect of VAT on the accuracy of preoperative-CT-evaluated T-staging of patients with gastric cancer.</p><p><strong>Results: </strong>The accurate-staging group had a significantly higher VAT area (134.64 ± 70.55 cm<sup>2</sup> vs 95.44 ± 66.18 cm<sup>2</sup>, P = 0.003) and significantly lower VAT density (-95.05 ± 12.28 Hounsfield Units [HU] vs - 89.68 ± 13.26 HU, P = 0.027) than the inaccurate-staging group. A low VAT area (P = 0.002) and tumor located in the upper stomach (P = 0.019) were significantly associated with and were independent risk factors for the error of CT-evaluated T-staging. Compared to a VAT area ≥ 81.04 cm<sup>2</sup>, which was used as a reference, the odds ratio (OR) of a VAT area < 81.04 cm<sup>2</sup> for the probability of T-staging mis-assessment was 4.455 (95% confidence interval [CI]: 1.728-11.485).</p><p><strong>Conclusions: </strong>A low VAT area in patients with gastric cancer had adverse effects on preoperative CT-evaluated T-staging.</p>\",\"PeriodicalId\":14691,\"journal\":{\"name\":\"Japanese Journal of Radiology\",\"volume\":\" \",\"pages\":\"656-665\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese Journal of Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s11604-024-01711-3\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11604-024-01711-3","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/28 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Influence of visceral adipose tissue on the accuracy of tumor T-staging of gastric cancer in preoperative CT.
Objectives: To evaluate the impact of the visceral adipose tissue (VAT) area and density on the accuracy of tumor T-staging of gastric cancer in preoperative computed tomography (CT).
Methods: This study included 136 patients with gastric cancer in our research center from January 2021 to June 2022. The patients were divided into two groups based on their postoperative pathological results: accurate-staging (matched T-staging evaluated by preoperative CT and postoperative pathology) and inaccurate-staging (unmatched T-staging evaluated by preoperative CT and postoperative pathology) groups. Preoperative CT was performed to assess the VAT area and density, and logistic regression was employed to evaluate the effect of VAT on the accuracy of preoperative-CT-evaluated T-staging of patients with gastric cancer.
Results: The accurate-staging group had a significantly higher VAT area (134.64 ± 70.55 cm2 vs 95.44 ± 66.18 cm2, P = 0.003) and significantly lower VAT density (-95.05 ± 12.28 Hounsfield Units [HU] vs - 89.68 ± 13.26 HU, P = 0.027) than the inaccurate-staging group. A low VAT area (P = 0.002) and tumor located in the upper stomach (P = 0.019) were significantly associated with and were independent risk factors for the error of CT-evaluated T-staging. Compared to a VAT area ≥ 81.04 cm2, which was used as a reference, the odds ratio (OR) of a VAT area < 81.04 cm2 for the probability of T-staging mis-assessment was 4.455 (95% confidence interval [CI]: 1.728-11.485).
Conclusions: A low VAT area in patients with gastric cancer had adverse effects on preoperative CT-evaluated T-staging.
期刊介绍：
Japanese Journal of Radiology is a peer-reviewed journal, officially published by the Japan Radiological Society. The main purpose of the journal is to provide a forum for the publication of papers documenting recent advances and new developments in the field of radiology in medicine and biology. The scope of Japanese Journal of Radiology encompasses but is not restricted to diagnostic radiology, interventional radiology, radiation oncology, nuclear medicine, radiation physics, and radiation biology. Additionally, the journal covers technical and industrial innovations. The journal welcomes original articles, technical notes, review articles, pictorial essays and letters to the editor. The journal also provides announcements from the boards and the committees of the society. Membership in the Japan Radiological Society is not a prerequisite for submission. Contributions are welcomed from all parts of the world.
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