神经肌肉接头文献中有哪些内容？

Q3 Medicine

Journal of Clinical Neuromuscular Disease Pub Date : 2024-12-01 DOI:10.1097/CND.0000000000000504

David Lacomis

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引用次数: 0

摘要

摘要：本文首先介绍了一系列有趣的儿童和成人先天性肌无力综合征 DOK7 变体患者。接下来介绍了自身免疫性重症肌无力（MG）的流行病学、医疗费用和住院情况。该部分讨论了一些关于较新治疗方法的研究，包括尼泊卡利单抗（nipocalimab）的二期试验以及使用其中一些药物的建议。一项大型试验强调了吡啶斯的明对肌肉特异性激酶 MG 的负面影响。随后还介绍了一项关于味觉障碍和脱发在 MG 中发生率的研究。本报告以 MG 和兰伯特-伊顿肌萎缩综合征的疾病负担为主题结束。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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What Is in the Neuromuscular Junction Literature?

Abstract: This update starts with an interesting series of children and adults with congenital myasthenic syndrome with a DOK7 variant. The next section is on autoimmune myasthenia gravis (MG) epidemiology, cost of care, and hospitalizations. A number of studies on the newer treatments are discussed including a phase 2 trial of nipocalimab and recommendations for using some of these drugs. A large trial emphasizing the negative effects of pyridostigmine in muscle-specific kinase MG is covered. A study on the incidence of taste disorders and alopecia in MG follows. The update ends with the topic of the burden of disease in MG and Lambert-Eaton myasthenic syndrome.

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来源期刊

Journal of Clinical Neuromuscular Disease Medicine-Medicine (all)

CiteScore

1.60

自引率

0.00%

发文量

期刊介绍： Journal of Clinical Neuromuscular Disease provides original articles of interest to physicians who treat patients with neuromuscular diseases, including disorders of the motor neuron, peripheral nerves, neuromuscular junction, muscle, and autonomic nervous system. Each issue highlights the most advanced and successful approaches to diagnosis, functional assessment, surgical intervention, pharmacologic treatment, rehabilitation, and more.