{"title":"用于 192Ir 近距离放射源周围剂量测量的光束质量校正系数。","authors":"Zoi Thrapsanioti, Vasiliki Peppa, Costas J Hourdakis, Pantelis Karaiskos, Aristea Lekatou, Evaggelos Pantelis","doi":"10.1002/acm2.14575","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To provide beam quality correction factors ( <math> <semantics><msub><mi>k</mi> <mrow><mi>Q</mi> <mo>,</mo> <mi>Q</mi> <mi>o</mi></mrow> </msub> <annotation>${k}_{Q,Qo}$</annotation></semantics> </math> ) for detectors used in <sup>192</sup>Ir brachytherapy dosimetry measurements.</p><p><strong>Materials and methods: </strong>Ten detectors were studied, including the PTW 30013 and Exrading12 Farmer large cavity chambers, seven medium (0.1-0.3 cm<sup>3</sup>) and small (< 0.1 cm<sup>3</sup>) cavity chambers, and a synthetic microdiamond detector. The k<sub>Q,Qo</sub> correction factors were calculated at distances from 1 to 10 cm away from an <sup>192</sup>Ir source, using the EGSnrc Monte Carlo (MC) code. All detectors were calibrated in a <sup>60</sup>Co 10 × 10 cm<sup>2</sup> reference field provided by standard calibration laboratories. The impact of the central electrode, stem and wall on the detectors' responses in <sup>192</sup>Ir photon energies was investigated. An experimental procedure was additionally applied for dose measurements around a microSelectron-v2 <sup>192</sup>Ir high dose rate (HDR) brachytherapy source using a motorized water phantom.</p><p><strong>Results: </strong>Farmer chambers underestimated the dose near the source due to signal volume averaging effects, resulting in k<sub>Q,Qo</sub> values ranging from 1.177 and 1.317 at 1 cm, decreasing with distance to between 0.980 and 1.005 at 10 cm. Small cavity volume detectors should be used close to the source. The k<sub>Q,Qo</sub> for the studied small and medium cavity volume detectors were found to be close to unity (within 1.3%), showing also a small dependence on source-to-detector distance, except for ion chambers containing high-Z materials in their construction. The presence of high-Z materials caused an overresponse in these detectors, resulting in k<sub>Q,Qo</sub> values ranging from 0.950 at 1 cm to 0.729 at 10 cm away from the source. A dose rate constant of (1.114 ± 0.023)cGyh<sup>-1</sup>U<sup>-1</sup> was found in agreement with the literature (within 0.5%).</p><p><strong>Conclusions: </strong>k<sub>Q,Qo</sub> values were calculated for dose measurements around <sup>192</sup>Ir brachytherapy sources. Farmer chambers should be preferred for measurements at increased distances, whereas small or medium cavity volume detectors, not containing high-Z materials, should be used close to the source.</p>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":" ","pages":"e14575"},"PeriodicalIF":2.0000,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Beam quality correction factors for dose measurements around <sup>192</sup>Ir brachytherapy sources.\",\"authors\":\"Zoi Thrapsanioti, Vasiliki Peppa, Costas J Hourdakis, Pantelis Karaiskos, Aristea Lekatou, Evaggelos Pantelis\",\"doi\":\"10.1002/acm2.14575\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To provide beam quality correction factors ( <math> <semantics><msub><mi>k</mi> <mrow><mi>Q</mi> <mo>,</mo> <mi>Q</mi> <mi>o</mi></mrow> </msub> <annotation>${k}_{Q,Qo}$</annotation></semantics> </math> ) for detectors used in <sup>192</sup>Ir brachytherapy dosimetry measurements.</p><p><strong>Materials and methods: </strong>Ten detectors were studied, including the PTW 30013 and Exrading12 Farmer large cavity chambers, seven medium (0.1-0.3 cm<sup>3</sup>) and small (< 0.1 cm<sup>3</sup>) cavity chambers, and a synthetic microdiamond detector. The k<sub>Q,Qo</sub> correction factors were calculated at distances from 1 to 10 cm away from an <sup>192</sup>Ir source, using the EGSnrc Monte Carlo (MC) code. All detectors were calibrated in a <sup>60</sup>Co 10 × 10 cm<sup>2</sup> reference field provided by standard calibration laboratories. The impact of the central electrode, stem and wall on the detectors' responses in <sup>192</sup>Ir photon energies was investigated. An experimental procedure was additionally applied for dose measurements around a microSelectron-v2 <sup>192</sup>Ir high dose rate (HDR) brachytherapy source using a motorized water phantom.</p><p><strong>Results: </strong>Farmer chambers underestimated the dose near the source due to signal volume averaging effects, resulting in k<sub>Q,Qo</sub> values ranging from 1.177 and 1.317 at 1 cm, decreasing with distance to between 0.980 and 1.005 at 10 cm. Small cavity volume detectors should be used close to the source. The k<sub>Q,Qo</sub> for the studied small and medium cavity volume detectors were found to be close to unity (within 1.3%), showing also a small dependence on source-to-detector distance, except for ion chambers containing high-Z materials in their construction. The presence of high-Z materials caused an overresponse in these detectors, resulting in k<sub>Q,Qo</sub> values ranging from 0.950 at 1 cm to 0.729 at 10 cm away from the source. A dose rate constant of (1.114 ± 0.023)cGyh<sup>-1</sup>U<sup>-1</sup> was found in agreement with the literature (within 0.5%).</p><p><strong>Conclusions: </strong>k<sub>Q,Qo</sub> values were calculated for dose measurements around <sup>192</sup>Ir brachytherapy sources. Farmer chambers should be preferred for measurements at increased distances, whereas small or medium cavity volume detectors, not containing high-Z materials, should be used close to the source.</p>\",\"PeriodicalId\":14989,\"journal\":{\"name\":\"Journal of Applied Clinical Medical Physics\",\"volume\":\" \",\"pages\":\"e14575\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-11-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Clinical Medical Physics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/acm2.14575\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Clinical Medical Physics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/acm2.14575","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Beam quality correction factors for dose measurements around 192Ir brachytherapy sources.
Purpose: To provide beam quality correction factors ( ) for detectors used in 192Ir brachytherapy dosimetry measurements.
Materials and methods: Ten detectors were studied, including the PTW 30013 and Exrading12 Farmer large cavity chambers, seven medium (0.1-0.3 cm3) and small (< 0.1 cm3) cavity chambers, and a synthetic microdiamond detector. The kQ,Qo correction factors were calculated at distances from 1 to 10 cm away from an 192Ir source, using the EGSnrc Monte Carlo (MC) code. All detectors were calibrated in a 60Co 10 × 10 cm2 reference field provided by standard calibration laboratories. The impact of the central electrode, stem and wall on the detectors' responses in 192Ir photon energies was investigated. An experimental procedure was additionally applied for dose measurements around a microSelectron-v2 192Ir high dose rate (HDR) brachytherapy source using a motorized water phantom.
Results: Farmer chambers underestimated the dose near the source due to signal volume averaging effects, resulting in kQ,Qo values ranging from 1.177 and 1.317 at 1 cm, decreasing with distance to between 0.980 and 1.005 at 10 cm. Small cavity volume detectors should be used close to the source. The kQ,Qo for the studied small and medium cavity volume detectors were found to be close to unity (within 1.3%), showing also a small dependence on source-to-detector distance, except for ion chambers containing high-Z materials in their construction. The presence of high-Z materials caused an overresponse in these detectors, resulting in kQ,Qo values ranging from 0.950 at 1 cm to 0.729 at 10 cm away from the source. A dose rate constant of (1.114 ± 0.023)cGyh-1U-1 was found in agreement with the literature (within 0.5%).
Conclusions: kQ,Qo values were calculated for dose measurements around 192Ir brachytherapy sources. Farmer chambers should be preferred for measurements at increased distances, whereas small or medium cavity volume detectors, not containing high-Z materials, should be used close to the source.
期刊介绍：
Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission.
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