纤维化间质性肺病的神经认知和神经精神影响。

IF 3.9 3区工程技术 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biomedicines Pub Date : 2024-11-10 DOI:10.3390/biomedicines12112572

Zsolt Vastag, Emanuela Tudorache, Daniel Traila, Ovidiu Fira-Mladinescu, Monica Steluta Marc, Cristian Oancea, Elena Cecilia Rosca

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引用次数: 0

摘要

间质性肺病（ILDs）患者伴有多种合并症，这些合并症对患者的临床疗效和存活率有重大影响。这些合并症中就包括神经系统损伤。本综述将重点介绍特发性肺纤维化、肉样瘤病、超敏性肺炎、结缔组织病等特定形式的纤维性 ILD 患者的认知功能、中枢神经系统 (CNS)、抑郁和焦虑方面的已知情况。本综述还介绍了神经认知功能障碍最常见的致病机制，以及识别这些机制的筛查方法和工具。

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Neurocognitive and Neuropsychiatric Implications of Fibrosing Interstitial Lung Diseases.

Patients with interstitial lung diseases (ILDs) associate a large variety of comorbidities that have a significant impact on their clinical outcomes and survival. Among these comorbidities is neurological impairment. This review highlights what is known about the cognitive function, central nervous system (CNS), depression, and anxiety in patients with specific forms of fibrosing ILDs, such as idiopathic pulmonary fibrosis, sarcoidosis, hypersensitivity pneumonitis, connective tissue diseases, etc. The most common pathogenic mechanisms for neurocognitive dysfunction as well as the screening methods and tools for their identification are also described in this review.

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来源期刊

Biomedicines Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology

CiteScore

5.20

自引率

8.50%

发文量

2823

审稿时长

8 weeks

期刊介绍： Biomedicines (ISSN 2227-9059; CODEN: BIOMID) is an international, scientific, open access journal on biomedicines published quarterly online by MDPI.