Cindy Mallet, Brice Ilharreborde, Marion Caseris, Anne-Laure Simon
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引用次数: 0
摘要
儿童髋关节化脓性关节炎(SAH)是一种常见的儿科疾病,必须立即确诊,因为需要适当的治疗才能确保良好的疗效。它主要影响两岁以下的儿童。致病菌与年龄有关。各年龄段最常见的病原体是金黄色葡萄球菌(S. aureus),而 Kingella kingae(Kk)则最常见于 6 个月至 4 岁的儿童。怀疑 SAH 的依据包括一系列临床、实验室和放射学(超声)标准。当患儿病情恶化时,核磁共振成像尤其有助于诊断并发症。只有在关节抽吸术发现存在细菌的证据时才能确诊。有针对性的 PCR 技术在很大程度上改进了 Kk 的微生物学诊断。临床表现差异很大,有的患儿患肢跛行,不能负重,伴有或不伴有发热,全身炎症非常轻微或不存在,提示为 Kk 引起的 SAH;有的患儿出现脓毒性休克,下肢准瘫痪。治疗主要包括关节引流和手术灌洗(开放式或关节镜),同时针对可能的感染原因进行经验性抗生素治疗。短期抗生素治疗广泛用于无并发症的 SAH 病例。功能性预后在很大程度上取决于诊断和开始治疗前的时间。功能性后遗症可能很严重(生长障碍、长期关节损伤)。证据等级:专家意见。
Treatment of septic arthritis of the hip in children.
Septic arthritis of the hip (SAH) in children is a common pediatric ailment that must be diagnosed immediately as proper treatment is needed to ensure good outcomes. It mostly affects children less than 2 years of age. The causative bacteria depend on age. The most widespread pathogen found at all ages is Staphylococcus aureus (S. aureus), while Kingella kingae (Kk) is most common in children 6 months to 4 years of age. SAH is suspected based on a wide set of clinical, laboratory and radiological (sonography) criteria. MRI is especially useful for diagnosing complications when the child's condition worsens. The diagnosis is only confirmed when joint aspiration finds evidence of bacteria being present. Targeted PCR techniques have largely improved the microbiological diagnosis of Kk. The clinical presentation varies greatly from a limp to prevent weightbearing on the affected leg in a small child with or without fever and very mild to non-existent systemic inflammation, suggestive of SAH due to Kk, to septic shock with quasi-paralysis of the lower limb. Treatment mainly consists of joint drainage and surgical lavage, open or arthroscopic, combined with empirical antibiotic therapy against the likely cause of the infection. A short course of antibiotics is widely used in uncomplicated cases of SAH. The functional prognosis depends highly on the time elapsed before the diagnosis and the start of treatment. Functional sequelae can be severe (growth disturbances, long-term joint damage). LEVEL OF EVIDENCE: Expert opinion.
期刊介绍:
Orthopaedics & Traumatology: Surgery & Research (OTSR) publishes original scientific work in English related to all domains of orthopaedics. Original articles, Reviews, Technical notes and Concise follow-up of a former OTSR study are published in English in electronic form only and indexed in the main international databases.