指南与共识:糖尿病空肠造口术--手术规范和专家共识(2023 年版)。

IF 4.2 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Ji-Wei Shen, Chun-Yong Ji, Xue-Dong Fang, Bo Yang, Tian Zhang, Zheng-Cai Li, Hua-Zhi Li, Zhi-Yi Liu, Jun Tang, Chuan-Wen Liao, Ji-Zhou Lu, Xuan Yang, Xin-Guo Zhang
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引用次数: 0

摘要

糖尿病(DM)是一组以胰岛素绝对或相对分泌不足导致高血糖为特征的疾病。一旦确诊,患者需要长期服用降糖药物进行治疗。目前,现有的一线降糖药物并不能有效治疗糖尿病及其并发症。过去,第一代和第二代减肥手术,如胃旁路手术和袖胃手术,对体重指数有严格要求。此外,手术后患者容易出现波动性低血糖、胃食管反流和倾倒综合征。因此,这类手术的疗效在一定程度上打了折扣。空肠造口术是针对DM患者的第三代手术,在不改变原有胃肠道结构的前提下,改善患者的糖脂代谢。与以往的减肥手术不同,临床观察发现空肠吻合术可延缓 DM 相关并发症的发生。此外,术后并发症较轻,不会影响患者的生活质量。根据多中心大样本的临床观察,我们的团队就空肠造口术的手术期和围手术期管理达成了共识,供临床研究人员参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Guidelines and consensus: Jejunoileostomy for diabetes mellitus-surgical norms and expert consensus (2023 version).

Diabetes mellitus (DM) is a group of diseases characterized by high blood glucose caused by insufficient absolute or relative secretion of insulin. Once diagnosed, patients need long-term treatment with hypoglycemic drugs. Currently, the existing first-line hypoglycemic drugs do not provide effective treatment for DM and its complications. In the past, the first generation and the second generation of weight loss surgery, such as gastric bypass and sleeve gastric surgery, had strict body mass index requirements. Moreover, post-surgery, patients are prone to fluctuating hypoglycemia, gastroesophageal reflux, and dumping syndrome. Hence, the curative effect of this type of surgery was compromised to a certain extent. Jejunoileostomy is a third-generation surgery for patients with DM, which has been shown to improve glucose and lipid metabolism, without changing the original gastrointestinal tract structure. Different from previous weight loss surgeries, jejunoileostomy has been clinically observed to delay the development of DM-related complications. Additionally, the postoperative complications are mild and do not affect the patient's quality of life. Based on our clinical observations from multi-center large samples, our team developed a consensus on the operative period and perioperative management of jejunoileostomy as a reference for clinical researchers.

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来源期刊
World Journal of Diabetes
World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-
自引率
2.40%
发文量
909
期刊介绍: The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.
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