[Evolution of systemic and local hemostatic agents in armed conflicts].

The issue of emergency care for traumatic bleeding is of particular relevance in modern medicine due to widespread military conflicts. This characterizes the need to summarize available data on hemostatic agents in combat conditions. This review of available literature is devoted to systemic and local hemostatic agents, as well as devices for temporary bleeding arrest. The most promising local hemostatic agents are chitosan-based products. Systemic hemostatic agents are represented by various forms and require further clinical trials. Modern tourniquets significantly reduce the mortality rate in extreme conditions and significantly exceed their historical counterparts in convenience and efficiency.