Vaddadi Vasudha Rani , G. Vasavi , P. Mano Paul , K. Sandhya Rani
{"title":"基于物联网的医疗保健系统利用分数蜣螂优化深度学习进行乳腺癌分类","authors":"Vaddadi Vasudha Rani , G. Vasavi , P. Mano Paul , K. Sandhya Rani","doi":"10.1016/j.compbiolchem.2024.108277","DOIUrl":null,"url":null,"abstract":"<div><div>Breast cancer classification plays a crucial role in healthcare, especially in the diagnosis and monitoring of patients. Traditional methods for classifying breast cancer based on histopathological images often suffer from limited accuracy, which can hinder early detection and treatment. Hence, this paper devises a novel Internet of Things (IoT) based healthcare system using SqueezeNet_Fractional Dung Beetle Optimization (Squeeze_FDBO) for breast cancer detection. Initially, IoT network is simulated, and routing of the histopathological images to the Base Station (BS) is established utilizing FDBO, which is obtained by combining Dung Beetle Optimizer (DBO), and the Fractional Calculus (FC). At BS, breast cancer classification is done, where input is first processed by a bilateral filter. Then, blood cell segmentation is effectuated using LadderNet, and then, feature extraction is performed. Finally, the multigrade classification of breast cancer is executed utilizing SqueezeNet tuned by FDBO. The efficiency of Squeeze_FDBO is validated using various performance measures, and it is found to record an accuracy of 0.919, sensitivity of 0.913, specificity of 0.923, Negative Predictive Value (NPV) of 0.920, and Positive Predictive Value (PPV) of 0.908, and a better routing performance with energy of 0.405 J, distance of 6.901 m, and delay of 0.650mS.</div></div>","PeriodicalId":10616,"journal":{"name":"Computational Biology and Chemistry","volume":"114 ","pages":"Article 108277"},"PeriodicalIF":2.6000,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"IoT based healthcare system using fractional dung beetle optimization enabled deep learning for breast cancer classification\",\"authors\":\"Vaddadi Vasudha Rani , G. Vasavi , P. Mano Paul , K. Sandhya Rani\",\"doi\":\"10.1016/j.compbiolchem.2024.108277\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Breast cancer classification plays a crucial role in healthcare, especially in the diagnosis and monitoring of patients. Traditional methods for classifying breast cancer based on histopathological images often suffer from limited accuracy, which can hinder early detection and treatment. Hence, this paper devises a novel Internet of Things (IoT) based healthcare system using SqueezeNet_Fractional Dung Beetle Optimization (Squeeze_FDBO) for breast cancer detection. Initially, IoT network is simulated, and routing of the histopathological images to the Base Station (BS) is established utilizing FDBO, which is obtained by combining Dung Beetle Optimizer (DBO), and the Fractional Calculus (FC). At BS, breast cancer classification is done, where input is first processed by a bilateral filter. Then, blood cell segmentation is effectuated using LadderNet, and then, feature extraction is performed. Finally, the multigrade classification of breast cancer is executed utilizing SqueezeNet tuned by FDBO. The efficiency of Squeeze_FDBO is validated using various performance measures, and it is found to record an accuracy of 0.919, sensitivity of 0.913, specificity of 0.923, Negative Predictive Value (NPV) of 0.920, and Positive Predictive Value (PPV) of 0.908, and a better routing performance with energy of 0.405 J, distance of 6.901 m, and delay of 0.650mS.</div></div>\",\"PeriodicalId\":10616,\"journal\":{\"name\":\"Computational Biology and Chemistry\",\"volume\":\"114 \",\"pages\":\"Article 108277\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-11-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computational Biology and Chemistry\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1476927124002652\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computational Biology and Chemistry","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1476927124002652","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
IoT based healthcare system using fractional dung beetle optimization enabled deep learning for breast cancer classification
Breast cancer classification plays a crucial role in healthcare, especially in the diagnosis and monitoring of patients. Traditional methods for classifying breast cancer based on histopathological images often suffer from limited accuracy, which can hinder early detection and treatment. Hence, this paper devises a novel Internet of Things (IoT) based healthcare system using SqueezeNet_Fractional Dung Beetle Optimization (Squeeze_FDBO) for breast cancer detection. Initially, IoT network is simulated, and routing of the histopathological images to the Base Station (BS) is established utilizing FDBO, which is obtained by combining Dung Beetle Optimizer (DBO), and the Fractional Calculus (FC). At BS, breast cancer classification is done, where input is first processed by a bilateral filter. Then, blood cell segmentation is effectuated using LadderNet, and then, feature extraction is performed. Finally, the multigrade classification of breast cancer is executed utilizing SqueezeNet tuned by FDBO. The efficiency of Squeeze_FDBO is validated using various performance measures, and it is found to record an accuracy of 0.919, sensitivity of 0.913, specificity of 0.923, Negative Predictive Value (NPV) of 0.920, and Positive Predictive Value (PPV) of 0.908, and a better routing performance with energy of 0.405 J, distance of 6.901 m, and delay of 0.650mS.
期刊介绍:
Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.
Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.
Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.