{"title":"融合生成式对抗网络和非负张量分解用于抑郁 fMRI 数据分析","authors":"Fengqin Wang , Hengjin Ke , Yunbo Tang","doi":"10.1016/j.ipm.2024.103961","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective:</h3><div>This study introduces a novel approach, F-GAN-NTD, which integrates Generative Adversarial Networks (GANs) with Non-negative Tensor Decomposition (NTD) theory to enhance the analysis of functional Magnetic Resonance Imaging (fMRI) data related to depression.</div></div><div><h3>Methods:</h3><div>F-GAN-NTD is applied to extract nonlinear non-negative factors from multidimensional fMRI tensor data, utilizing Deep-NTD technology to generate factor matrices that capture latent structures and dynamic features. A multi-view neural network architecture processes these factor matrices from all modalities simultaneously, enabling comprehensive pattern discrimination between depression patients and healthy controls. The method is tested on the Closed Eyes Depression fMRI (CEDF) and Strategic Research Program for Brain Sciences (SRPBS) datasets.</div></div><div><h3>Results:</h3><div>The F-GAN-NTD method demonstrates significant improvements in fMRI data classification, outperforming traditional approaches. It also effectively restores incomplete fMRI tensor data and reveals abnormal brain network connections, offering insights into the pathophysiological mechanisms of depression.</div></div><div><h3>Conclusions:</h3><div>F-GAN-NTD enhances the extraction of meaningful features from fMRI data, improving classification performance and providing a deeper understanding of depression-related brain abnormalities. The integration across modalities contributes to a more comprehensive analysis of depression.</div></div>","PeriodicalId":50365,"journal":{"name":"Information Processing & Management","volume":"62 2","pages":"Article 103961"},"PeriodicalIF":7.4000,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fusion of generative adversarial networks and non-negative tensor decomposition for depression fMRI data analysis\",\"authors\":\"Fengqin Wang , Hengjin Ke , Yunbo Tang\",\"doi\":\"10.1016/j.ipm.2024.103961\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective:</h3><div>This study introduces a novel approach, F-GAN-NTD, which integrates Generative Adversarial Networks (GANs) with Non-negative Tensor Decomposition (NTD) theory to enhance the analysis of functional Magnetic Resonance Imaging (fMRI) data related to depression.</div></div><div><h3>Methods:</h3><div>F-GAN-NTD is applied to extract nonlinear non-negative factors from multidimensional fMRI tensor data, utilizing Deep-NTD technology to generate factor matrices that capture latent structures and dynamic features. A multi-view neural network architecture processes these factor matrices from all modalities simultaneously, enabling comprehensive pattern discrimination between depression patients and healthy controls. The method is tested on the Closed Eyes Depression fMRI (CEDF) and Strategic Research Program for Brain Sciences (SRPBS) datasets.</div></div><div><h3>Results:</h3><div>The F-GAN-NTD method demonstrates significant improvements in fMRI data classification, outperforming traditional approaches. It also effectively restores incomplete fMRI tensor data and reveals abnormal brain network connections, offering insights into the pathophysiological mechanisms of depression.</div></div><div><h3>Conclusions:</h3><div>F-GAN-NTD enhances the extraction of meaningful features from fMRI data, improving classification performance and providing a deeper understanding of depression-related brain abnormalities. The integration across modalities contributes to a more comprehensive analysis of depression.</div></div>\",\"PeriodicalId\":50365,\"journal\":{\"name\":\"Information Processing & Management\",\"volume\":\"62 2\",\"pages\":\"Article 103961\"},\"PeriodicalIF\":7.4000,\"publicationDate\":\"2024-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Information Processing & Management\",\"FirstCategoryId\":\"94\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0306457324003200\",\"RegionNum\":1,\"RegionCategory\":\"管理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"COMPUTER SCIENCE, INFORMATION SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Information Processing & Management","FirstCategoryId":"94","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0306457324003200","RegionNum":1,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
Fusion of generative adversarial networks and non-negative tensor decomposition for depression fMRI data analysis
Objective:
This study introduces a novel approach, F-GAN-NTD, which integrates Generative Adversarial Networks (GANs) with Non-negative Tensor Decomposition (NTD) theory to enhance the analysis of functional Magnetic Resonance Imaging (fMRI) data related to depression.
Methods:
F-GAN-NTD is applied to extract nonlinear non-negative factors from multidimensional fMRI tensor data, utilizing Deep-NTD technology to generate factor matrices that capture latent structures and dynamic features. A multi-view neural network architecture processes these factor matrices from all modalities simultaneously, enabling comprehensive pattern discrimination between depression patients and healthy controls. The method is tested on the Closed Eyes Depression fMRI (CEDF) and Strategic Research Program for Brain Sciences (SRPBS) datasets.
Results:
The F-GAN-NTD method demonstrates significant improvements in fMRI data classification, outperforming traditional approaches. It also effectively restores incomplete fMRI tensor data and reveals abnormal brain network connections, offering insights into the pathophysiological mechanisms of depression.
Conclusions:
F-GAN-NTD enhances the extraction of meaningful features from fMRI data, improving classification performance and providing a deeper understanding of depression-related brain abnormalities. The integration across modalities contributes to a more comprehensive analysis of depression.
期刊介绍:
Information Processing and Management is dedicated to publishing cutting-edge original research at the convergence of computing and information science. Our scope encompasses theory, methods, and applications across various domains, including advertising, business, health, information science, information technology marketing, and social computing.
We aim to cater to the interests of both primary researchers and practitioners by offering an effective platform for the timely dissemination of advanced and topical issues in this interdisciplinary field. The journal places particular emphasis on original research articles, research survey articles, research method articles, and articles addressing critical applications of research. Join us in advancing knowledge and innovation at the intersection of computing and information science.