稳定型心绞痛:病理生理学、诊断及其治疗综述》(Stable Angina Pectoris: A Review of Pathophysiology, Diagnosis, and Its Management)。

Q3 Medicine
Anurag Sharma, Tushor Roy, Paramartha Bhattacharya, Dinesh Agarwal, Rohit Kumar, Syed Mujtaba Hussain Naqvi, Rajan Mittal
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引用次数: 0

摘要

印度正处于心血管疾病(CVD)即将流行的风口浪尖。快速的城市化、工业化和全球化引发了这一流行病。冠状动脉疾病(CAD)和缺血性心脏病(IHD)在临床上表现为心绞痛(胸痛和不适)。尽管冠状动脉疾病的治疗方法在不断进步,但在中低收入国家,人们对风险因素和疾病缺乏认识、医疗服务的可及性和可负担性仍是主要问题。在印度,每年因心血管疾病死亡的人数超过 700 万。患者、医生和医疗保健提供者之间需要积极合作,以确定早期和充分使用生活方式、药物、一级和二级预防措施。抗心绞痛治疗方案分为一线药物(钙通道阻滞剂(CCB)、β-受体阻滞剂和短效硝酸盐)和二线药物(伊伐布雷定、尼可地尔、雷诺拉嗪和曲美他嗪)。本综述讨论了治疗心绞痛的不同 CCBs(二氢吡啶类(DHPs)或非二氢吡啶类)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stable Angina Pectoris: A Review of Pathophysiology, Diagnosis, and Its Management.

India is at the cusp of an impending epidemic of cardiovascular diseases (CVD). It has been triggered by rapid urbanization, industrialization, and globalization. Coronary artery disease (CAD) and ischemic heart disease (IHD) clinically present as angina pectoris (chest pain and discomfort). Despite advances in treatment options for CAD, a lack of awareness of risk factors and disease, access to healthcare, and affordability are the primary concerns in low- and middle-income countries. In India, CAD results in >7 million deaths annually. There is a need for active collaboration between patients, physicians, and healthcare providers to identify the early and adequate use of lifestyle, pharmacological, and primary and secondary preventive measures. Antianginal treatment options are categorized as first line (calcium channel blockers (CCBs), β-blockers, and short-acting nitrates) and second line (ivabradine, nicorandil, ranolazine, and trimetazidine) drugs. This review discusses different CCBs (dihydropyridines (DHPs) or nondihydropyridines) for the management of angina pectoris.

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CiteScore
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