Bruno Sousa, Maria Bessa, Filipa L de Mendonça, Pedro G Ferreira, Alexandra Moreira, Isabel Pereira-Castro
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APAtizer: a tool for alternative polyadenylation analysis of RNA-Seq data.
Summary: APAtizer is a tool designed to analyze alternative polyadenylation events on RNA-sequencing data. The tool handles different file formats, including BAM, htseq and DaPars bedGraph files. It provides a user-friendly interface that allows users to generate informative visualizations, including Volcano plots, heatmaps and gene lists. These outputs allow the user to retrieve useful biological insights such as the occurrence of polyadenylation events when comparing two biological conditions. Additionally, it can perform differential gene expression, gene ontology analysis, visualization of Venn diagram intersections and correlation analysis.
Availability and implementation: Source code and example case studies for APAtizer are available at https://github.com/GeneRegulationi3S/APAtizer/.
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